ID   A0A1N6XZ25_9GAMM        Unreviewed;       334 AA.
AC   A0A1N6XZ25;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=UDP-N-acetylglucosamine 4,6-dehydratase {ECO:0000313|EMBL:SIR07536.1};
GN   ORFNames=SAMN05880558_108133 {ECO:0000313|EMBL:SIR07536.1};
OS   Aeromonas sp. RU39B.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=1907416 {ECO:0000313|EMBL:SIR07536.1, ECO:0000313|Proteomes:UP000186911};
RN   [1] {ECO:0000313|EMBL:SIR07536.1, ECO:0000313|Proteomes:UP000186911}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RU39B {ECO:0000313|EMBL:SIR07536.1,
RC   ECO:0000313|Proteomes:UP000186911};
RA   Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=UDP-alpha-D-glucose = UDP-alpha-D-galactose;
CC         Xref=Rhea:RHEA:22168, ChEBI:CHEBI:58885, ChEBI:CHEBI:66914;
CC         EC=5.1.3.2; Evidence={ECO:0000256|ARBA:ARBA00000083};
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; FTMJ01000008; SIR07536.1; -; Genomic_DNA.
DR   RefSeq; WP_076576079.1; NZ_FTMJ01000008.1.
DR   AlphaFoldDB; A0A1N6XZ25; -.
DR   STRING; 1907416.SAMN05880558_108133; -.
DR   InParanoid; A0A1N6XZ25; -.
DR   OrthoDB; 9803111at2; -.
DR   Proteomes; UP000186911; Unassembled WGS sequence.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   InterPro; IPR020025; PseB.
DR   NCBIfam; TIGR03589; PseB; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   PANTHER; PTHR43318:SF2; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE (INVERTING); 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
FT   DOMAIN          7..279
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   334 AA;  37425 MW;  536D1E84C53DE3E3 CRC64;
     MFDNKSILIT GGTGSFGKML VRTILARYKP KRLIIFSRDE LKQFEMQQIY NDPCMRYFIG
     DVRDANRLTM AMRGVDIVVH AAALKQVPAA EYNPMECIKT NIHGAENVIQ AALLNQVKKV
     IALSTDKAAN PINLYGATKL ASDKLFVAAN NIAGQDPTRF AVVRYGNVVG SRGSVVPFFQ
     KLIDQGKHSL PITHAEMTRF WITLQQGVDF VLRNFERMKG GEIFVPKLPS VRITELAKAM
     APELSHDIIG IRPGEKLHEV MCPADDSYHT FEFDDFFVIG PTINFNNRNN DFSRTAAGEN
     GQAVAQGFEY NSRDNPDFLT IEQLMALNKQ VVFE
//