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Database: UniProt
Entry: A0A1N6XZP8_9GAMM
LinkDB: A0A1N6XZP8_9GAMM
Original site: A0A1N6XZP8_9GAMM 
ID   A0A1N6XZP8_9GAMM        Unreviewed;       358 AA.
AC   A0A1N6XZP8;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   08-MAY-2019, entry version 7.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=SAMN05880558_108143 {ECO:0000313|EMBL:SIR07895.1};
OS   Aeromonas sp. RU39B.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=1907416 {ECO:0000313|EMBL:SIR07895.1, ECO:0000313|Proteomes:UP000186911};
RN   [1] {ECO:0000313|EMBL:SIR07895.1, ECO:0000313|Proteomes:UP000186911}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RU39B {ECO:0000313|EMBL:SIR07895.1,
RC   ECO:0000313|Proteomes:UP000186911};
RA   Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; FTMJ01000008; SIR07895.1; -; Genomic_DNA.
DR   RefSeq; WP_076576088.1; NZ_FTMJ01000008.1.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000186911; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000186911};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186911};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       41    340       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   358 AA;  39489 MW;  A22C42E96567A04E CRC64;
     MHKDALTDIH IQSEQVMITP AELKAKLPVS EHALAFIQQA RHTISNIIHR RDHRLLVICG
     PCSIHDIDAA KEYATRLKAL HDAYRDSLYI VMRVYFEKPR TTVGWKGFIN DPKLDGTFDI
     EQGLHQAREL LCWLAELELP LATEALDPIS PQYLADLFSW SAIGARTTES QTHREMASGL
     SMPVGFKNGT DGNLGTAINA MRAASSSHAF MGINQQGQVA LLQTQGNPDG HVILRGGKAP
     NYDSVNVSLA EEAMEQAGLT PCLVVDCSHG NSNKDYRLQP KVADNVIRQI QEGNKAIIGL
     MLESHLDEGN QSSEQPRECM RYGVSITDAC IGWESTAELL ERANRELGSA LKARRQSA
//
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