ID   A0A1N6YPJ3_9FLAO        Unreviewed;       621 AA.
AC   A0A1N6YPJ3;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=DNA topoisomerase (ATP-hydrolyzing) {ECO:0000256|ARBA:ARBA00012895};
DE            EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
GN   ORFNames=SAMN05421797_10788 {ECO:0000313|EMBL:SIR16515.1};
OS   Maribacter ulvicola.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Maribacter.
OX   NCBI_TaxID=228959 {ECO:0000313|EMBL:SIR16515.1, ECO:0000313|Proteomes:UP000186953};
RN   [1] {ECO:0000313|EMBL:SIR16515.1, ECO:0000313|Proteomes:UP000186953}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15366 {ECO:0000313|EMBL:SIR16515.1,
RC   ECO:0000313|Proteomes:UP000186953};
RA   Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP-dependent breakage, passage and rejoining of double-
CC         stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FTMA01000007; SIR16515.1; -; Genomic_DNA.
DR   RefSeq; WP_076549942.1; NZ_FTMA01000007.1.
DR   AlphaFoldDB; A0A1N6YPJ3; -.
DR   STRING; 228959.SAMN05421797_10788; -.
DR   OrthoDB; 9802808at2; -.
DR   Proteomes; UP000186953; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   CDD; cd01030; TOPRIM_TopoIIA_like; 1.
DR   Gene3D; 3.30.230.10; -; 1.
DR   Gene3D; 3.40.50.670; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR   InterPro; IPR001241; Topo_IIA.
DR   InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR   InterPro; IPR013759; Topo_IIA_B_C.
DR   InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR   InterPro; IPR018522; TopoIIA_CS.
DR   InterPro; IPR006171; TOPRIM_domain.
DR   PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR   PANTHER; PTHR45866:SF2; DNA TOPOISOMERASE (ATP-HYDROLYZING); 1.
DR   Pfam; PF00204; DNA_gyraseB; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF01751; Toprim; 1.
DR   PRINTS; PR00418; TPI2FAMILY.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00433; TOP2c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR   SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR   PROSITE; PS00177; TOPOISOMERASE_II; 1.
DR   PROSITE; PS50880; TOPRIM; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:SIR16515.1}.
FT   DOMAIN          409..515
FT                   /note="Toprim"
FT                   /evidence="ECO:0000259|PROSITE:PS50880"
FT   COILED          346..373
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   621 AA;  70795 MW;  BBF7A5CD1F3E9ECC CRC64;
     MSQDPTQYTE DNIRSLDWKE HIRLRPGMYI GKLGDGSSAD DGIYILLKEV IDNCIDEFVM
     GAGKTIEISI KDKVVKVRDY GRGIPLGKVV DVVSKMNTGG KYDSRAFKKS VGLNGVGTKA
     VNALSSFFEV QSSRDSQLKT AQFSSGNLES EVGPEDTGKR KGTKVTFIPD EAIFKNYKYR
     NEYVERMLKN YVYLNPGLTI VFNGEKFHSE NGLKDLLEDN NNVDDMLYPV IHLKGDDIEV
     AITHSRTQYS EEYHSFVNGQ HTTHGGTHQA AFREAIVKTI RDFYGKTYDA SDIRKSIISA
     ISIKVMEPVF ESQTKTKLGS TDMGGNFPTV RTYINEFIGK YLDNYLHKNA DTADKLQRKI
     MMAEKERKEL SGIRKLARDR AKKASLHNKK LRDCRVHLSD MKHDRRLESA LFITEGDSAS
     GSITKSRDVN TQAVFSLKGK PLNSYGMSKK IVYENEEFNL LQAALNIEES IEDLRYNNII
     IATDADVDGM HIRLLLITFF LQFFPELIKE NHLYILQTPL FRVRNKKETV YCYSDEERQK
     AINKLSGKPE ITRFKGLGEI SPDEFRHFIG DDIRLEPIML DKAMSIEELL SFYMGKNTPD
     RQKFIINNLK VEVDLIEDKV V
//