ID   A0A1N6ZI04_9ACTN        Unreviewed;       407 AA.
AC   A0A1N6ZI04;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Ribonuclease D {ECO:0000313|EMBL:SIR26404.1};
GN   ORFNames=SAMN05421833_107149 {ECO:0000313|EMBL:SIR26404.1};
OS   Microbispora rosea.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Microbispora.
OX   NCBI_TaxID=58117 {ECO:0000313|EMBL:SIR26404.1, ECO:0000313|Proteomes:UP000186096};
RN   [1] {ECO:0000313|EMBL:SIR26404.1, ECO:0000313|Proteomes:UP000186096}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12950 {ECO:0000313|EMBL:SIR26404.1,
RC   ECO:0000313|Proteomes:UP000186096};
RA   Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FTNI01000007; SIR26404.1; -; Genomic_DNA.
DR   RefSeq; WP_076434669.1; NZ_FTNI01000007.1.
DR   AlphaFoldDB; A0A1N6ZI04; -.
DR   STRING; 58117.SAMN05421833_107149; -.
DR   OrthoDB; 144122at2; -.
DR   Proteomes; UP000186096; Unassembled WGS sequence.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR   CDD; cd06142; RNaseD_exo; 1.
DR   Gene3D; 1.10.150.80; HRDC domain; 2.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR   InterPro; IPR041605; Exo_C.
DR   InterPro; IPR010997; HRDC-like_sf.
DR   InterPro; IPR002121; HRDC_dom.
DR   InterPro; IPR044876; HRDC_dom_sf.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR47649; RIBONUCLEASE D; 1.
DR   PANTHER; PTHR47649:SF1; RIBONUCLEASE D; 1.
DR   Pfam; PF01612; DNA_pol_A_exo1; 1.
DR   Pfam; PF18305; DNA_pol_A_exoN; 1.
DR   Pfam; PF00570; HRDC; 1.
DR   SMART; SM00474; 35EXOc; 1.
DR   SMART; SM00341; HRDC; 1.
DR   SUPFAM; SSF47819; HRDC-like; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50967; HRDC; 1.
PE   4: Predicted;
FT   DOMAIN          222..302
FT                   /note="HRDC"
FT                   /evidence="ECO:0000259|PROSITE:PS50967"
FT   REGION          299..321
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   407 AA;  44366 MW;  998363970EC8E215 CRC64;
     MTEPVIQPLL EPREGIPPVI EDSAALAAAV DAFARGSGPV AVDAERASGY RYSGRAYLVQ
     LRRAGAGTAL IDPIKCPDLS ALDEAVRDAE IVLHAANQDL PCLAELGFRP GRLFDTELAG
     RLLGYERVGL GTMVELVLGL RLEKGHSAAD WSARPLPEDW LRYAALDVEV LVELRDVLHD
     ELSGTGKLEW ALEEFASILA APAHPPRTDP WRRTSGIHRV RTLRGLAVVR ELWTLRDEIA
     RESDLAPGRV LPDAAIVQAA LDQPRTTKAL TEITPFVGRS ARRHLNDWLT AVNRARTMPE
     ASLPQPVGPG DGPPPANRWA DRDPAAAKRL AAARAVVAAL ADEHRMPTEN LLQPDAVRRL
     TWEPPAPISE ETVAARLRAL GAREWQIGLT VHPLVKALER LEIKGEV
//