ID A0A1N7EC85_9GAMM Unreviewed; 896 AA.
AC A0A1N7EC85;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=DNA translocase FtsK {ECO:0000256|ARBA:ARBA00020887};
GN ORFNames=SAMN02745664_10447 {ECO:0000313|EMBL:SIR85762.1};
OS Moraxella cuniculi DSM 21768.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Moraxella.
OX NCBI_TaxID=1122245 {ECO:0000313|EMBL:SIR85762.1, ECO:0000313|Proteomes:UP000187495};
RN [1] {ECO:0000313|Proteomes:UP000187495}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21768 {ECO:0000313|Proteomes:UP000187495};
RA Varghese N., Submissions S.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
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DR EMBL; FTNU01000004; SIR85762.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1N7EC85; -.
DR STRING; 34061.B0189_07040; -.
DR Proteomes; UP000187495; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000187495};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 544..759
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 271..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 562..569
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 896 AA; 98500 MW; A4FABD2F2769EBD9 CRC64;
MKTLSLNQFI TPKKMSLFGQ LLLTVIGTVL LVFLFLALLS YDKTDSAWSH IGSNPEIANV
AGRMGAWVAD ILHTFFGYGA WFLVLVLAYE LARLWWLHAK LLWVLRVSAY ALLLAFISAL
LAYMGDFRDN GLAASLGGAM GFELQKNLVI NLGASVTALA LIALIGIIAA LSFEIRWANV
AAMIMDWVGQ ARPKADNEQT PVAEVPKQPV ADDVDEPIDD VVQAHNHHGA LESFLCHSGL
RDELLAKRQA EQDAAAQRVL DEQIALQTQA ISLSEQMPSD DKNPAWQYES DDEPNPYSTV
ADEHIINEAS ISLALTDEPK IQPDEAVPST VDRYNQLGKL RIDSADVDAN HQPQTTVSAK
PYEPMPELVD GLSDEPNDTA AWADEPSQAG GQPKSYAMGK LAYRMSLSPI PELTLLDTPD
YQNKPKVSEA KLKESSELLE IKLQEYNIQA QVMAATVGPV VTRFEVALAA GVKASRVTRE
ARDLARNMLK ESLRVVEVIP GKPYIGIEVP NEKREMVRLI ELLDTPDYQD PDKQIAIAVG
KDISGKVVIA DLAKAPHMLV AGTTGSGKSV LVNSFLLSML LKYTPDELKL VLIDPKQLEL
ANYNDIPHLL TPVITDMQDA VAALTWCVNE MERRYRLMSK LRVRKIAEFN KKIIQAEQSG
EPIYDPLWQA NDSVSQSKPP KLKTLPIIVI VADEFADMIM QLGKTAEEPI VRLAQKARAA
GIHLLLATQR PTVNVVTGLI KANVPSRVAL RVNTKVDSRT IIEEGGAEDM LGNGDMMFIA
PGKNSAERVH GAYVDDDEVN RVCDAWRERG SPDYIDLSES YTFDGEGSGD TSSVADGDQL
YEAAAAYVVE TRKPSISSVQ RKFSIGYNRA ARLLDQMQER GLVSAMDNSG KRQLLL
//
