ID A0A1N7ECX8_9EURY Unreviewed; 405 AA.
AC A0A1N7ECX8;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Mechanosensitive ion channel {ECO:0000313|EMBL:APX96500.1, ECO:0000313|EMBL:SIR86002.1};
GN ORFNames=BB347_07655 {ECO:0000313|EMBL:APX96500.1}, SAMN05421809_2623
GN {ECO:0000313|EMBL:SIR86002.1};
OS Natronorubrum daqingense.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronorubrum.
OX NCBI_TaxID=588898 {ECO:0000313|EMBL:SIR86002.1, ECO:0000313|Proteomes:UP000185687};
RN [1] {ECO:0000313|EMBL:APX96500.1, ECO:0000313|Proteomes:UP000187321}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JX313 {ECO:0000313|EMBL:APX96500.1,
RC ECO:0000313|Proteomes:UP000187321};
RA Shuang W.;
RT "Complete genome sequence of Haloterrigena daqingensis type strain
RT (JX313T).";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SIR86002.1, ECO:0000313|Proteomes:UP000185687}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.8909 {ECO:0000313|EMBL:SIR86002.1,
RC ECO:0000313|Proteomes:UP000185687};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; CP019327; APX96500.1; -; Genomic_DNA.
DR EMBL; FTNP01000003; SIR86002.1; -; Genomic_DNA.
DR RefSeq; WP_076582451.1; NZ_FTNP01000003.1.
DR AlphaFoldDB; A0A1N7ECX8; -.
DR STRING; 588898.BB347_07655; -.
DR GeneID; 30955808; -.
DR KEGG; hda:BB347_07655; -.
DR OrthoDB; 31543at2157; -.
DR Proteomes; UP000185687; Unassembled WGS sequence.
DR Proteomes; UP000187321; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR045275; MscS_archaea/bacteria_type.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30221; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR PANTHER; PTHR30221:SF1; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000185687};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 183..254
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 261..344
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
FT REGION 364..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..405
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 45198 MW; 6D200ED6DEE0A8BB CRC64;
MTAFYSNWVQ EVLYGSPPLQ LLTSIAVIFA LVALFALTRG LRRLLGDRYT RNFAEAVEMA
VFAGSIVVAA YVLADIWALS FVFGEVLDVI FVDRFTGIRG AVSVAILTTG YLLVRMVNRS
FDRLYREDLI TNHQKEVAYH TADAGIFVIA GLVIMSIWGI ELTNLILSAG VVSAVFGLAA
QKTVAAFVAG FLLLFTRPFR AGDWIEVANQ NDRKTAGIVQ DITISHTKIR TFNDEHVLVP
NDELTSNELI NYSRSNRLRV DVELGVDYDT NLNRARTVIR NAVDGIDIIS PLKEPQVVSK
RFGDSAVVLE LQFWIEDPKR RRVWQAQTVV IDAIKNAFEQ EAITIPYPQR THQSRNDRGF
RVASAASMEG DGRLESDRGE PRTSTEPETK GDAVEPAQDR EVTNR
//
