ID   A0A1N7GZX3_9ACTN        Unreviewed;       399 AA.
AC   A0A1N7GZX3;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Uncharacterized membrane-anchored protein {ECO:0000313|EMBL:SIS17998.1};
GN   ORFNames=SAMN05421833_13485 {ECO:0000313|EMBL:SIS17998.1};
OS   Microbispora rosea.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Microbispora.
OX   NCBI_TaxID=58117 {ECO:0000313|EMBL:SIS17998.1, ECO:0000313|Proteomes:UP000186096};
RN   [1] {ECO:0000313|EMBL:SIS17998.1, ECO:0000313|Proteomes:UP000186096}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12950 {ECO:0000313|EMBL:SIS17998.1,
RC   ECO:0000313|Proteomes:UP000186096};
RA   Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FTNI01000034; SIS17998.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1N7GZX3; -.
DR   STRING; 58117.SAMN05421833_13485; -.
DR   OrthoDB; 5169996at2; -.
DR   Proteomes; UP000186096; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004788; F:thiamine diphosphokinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.10240; Thiamin pyrophosphokinase, catalytic domain; 1.
DR   InterPro; IPR047795; Put_SteA-like.
DR   InterPro; IPR022215; SteA-like_C.
DR   InterPro; IPR007371; TPK_catalytic.
DR   InterPro; IPR036759; TPK_catalytic_sf.
DR   NCBIfam; NF040608; division_SteA; 1.
DR   Pfam; PF12555; SteA-like_C; 1.
DR   Pfam; PF04263; TPK_catalytic; 1.
DR   SUPFAM; SSF63999; Thiamin pyrophosphokinase, catalytic domain; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        354..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        378..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          214..247
FT                   /note="Thiamin pyrophosphokinase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF04263"
FT   DOMAIN          340..391
FT                   /note="SteA-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12555"
SQ   SEQUENCE   399 AA;  42985 MW;  0B4E1B7DD11B43AD CRC64;
     MMKVPSLNVP GLRRRKADGL PGVTAVARID RRTKRLTKRL KPGEIAIIDH VDIDRVSGEA
     LVACGVAAVV NVAASISGRY PNLGPQILID AGIPLIDNAS PELFERIADG DVIRVHDGMV
     YLGEELVGKG QPQTAESVEA AMTEARAGLA VQIEAFAANT MEYVRRERDL LIDGVGVPDI
     RTSLENRHAL IVVRGYHYKE DIATLRPYIR EYRPVLIGVD GGADALLDAG YVPDIIVGDF
     DSVSEKALCC GAELVVHAYR DGRAPGLERV RKLGQEAVVF PATGTSEDIA MLLSDDKGAT
     LIVAVGTHWT LDEFLDKGRS GAASTFLTRL RVGSKLVDAK GVSRLYRSRI STSSLLLLVA
     TTLVTIGVVL SVSPIGQVWL NGLRVAWNGF IFWLVGLFS
//