ID   A0A1N7HMY4_9RHOB        Unreviewed;       735 AA.
AC   A0A1N7HMY4;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Sulfite reductase (NADPH) flavoprotein alpha-component {ECO:0000313|EMBL:SIS26070.1};
GN   ORFNames=SAMN05421666_3451 {ECO:0000313|EMBL:SIS26070.1};
OS   Roseovarius nanhaiticus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Roseovarius.
OX   NCBI_TaxID=573024 {ECO:0000313|EMBL:SIS26070.1, ECO:0000313|Proteomes:UP000186019};
RN   [1] {ECO:0000313|EMBL:SIS26070.1, ECO:0000313|Proteomes:UP000186019}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 29590 {ECO:0000313|EMBL:SIS26070.1,
RC   ECO:0000313|Proteomes:UP000186019};
RA   Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
CC         Evidence={ECO:0000256|ARBA:ARBA00001917};
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DR   EMBL; FTNV01000005; SIS26070.1; -; Genomic_DNA.
DR   RefSeq; WP_028288619.1; NZ_FTNV01000005.1.
DR   AlphaFoldDB; A0A1N7HMY4; -.
DR   STRING; 573024.SAMN05216208_3526; -.
DR   OrthoDB; 9816402at2; -.
DR   Proteomes; UP000186019; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd06201; SiR_like2; 1.
DR   Gene3D; 3.40.50.360; -; 1.
DR   Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 1.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR008254; Flavodoxin/NO_synth.
DR   InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR   InterPro; IPR029039; Flavoprotein-like_sf.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR   InterPro; IPR005625; PepSY-ass_TM.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   PANTHER; PTHR19384:SF17; NADPH--CYTOCHROME P450 REDUCTASE; 1.
DR   PANTHER; PTHR19384; NITRIC OXIDE SYNTHASE-RELATED; 1.
DR   Pfam; PF00258; Flavodoxin_1; 1.
DR   Pfam; PF00175; NAD_binding_1; 1.
DR   Pfam; PF03929; PepSY_TM; 1.
DR   PRINTS; PR00371; FPNCR.
DR   SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR   SUPFAM; SSF52218; Flavoproteins; 1.
DR   SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
DR   PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE   4: Predicted;
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186019};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        122..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        287..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          333..469
FT                   /note="Flavodoxin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50902"
FT   DOMAIN          485..598
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51384"
SQ   SEQUENCE   735 AA;  77628 MW;  D720616DD9032C07 CRC64;
     MIRTLHRWPG LLALALVTIL SLSGAALSVF PAVERITAPQ VETGLTVATL AERIQVVYPG
     VEQIRRSPSG RITAYWFDQG APGAAVIDPA TGAGVASADP NQALRWLTNF HRSLFLGDGG
     RIAMAAGAAA MLVLSLSGAM LVVRRAGGWR HWFASLRGPF TGRLHVEIAR IAVIGLVLSS
     TTALWMTAST FDLLPDGGVL PADPTEVSGE IGFALDQMAT LLQTPVAELR ELSFPYPGDA
     TDVFTLKTDR GTGYLDQGTG ALVAWADLTG WERVSETIYM LHTGQGAAML GLVLGMMALG
     VPAMGVTGVL IWLAGRRGRP RIRGNQPAGR AETIILVGSE GGSTWGFAAT LHAALTAAGQ
     GVHVGPMSGF APERYARAER IIVLAATYGD GAAPASAKGL LDRMNASAPA PDIPMALLGF
     GDRSFPSYCA FAKAVAAAAQ AKGWAELMPL DTIDRQSPQD FARWGRALGE VLGISLELSH
     QPVSPRTETL TLVSRRNYGA EMQAGAAILR FALPRATPWQ RLTGTGFARF QAGDLIGVLP
     QGSPMPRLYS LASGRRDGFV EIVVRKHPGG LASGQLTALE PGDTVRAFLR RNPGFHAGRG
     LTPLILIGAG TGIGPLAGFI RGNARHRPVH LFFGMRHADS DFFYGEEMPG WQAEGRLTRL
     VTAVSRGARR SYVQDALRAD AAQVARLICD GARVMVCGGR DMATGVSDAL AEILAPAGLT
     PAVLKAEGRY VEDVY
//