ID A0A1N7K2X6_9GAMM Unreviewed; 898 AA.
AC A0A1N7K2X6;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05421686_102305 {ECO:0000313|EMBL:SIS55897.1};
OS Thalassolituus maritimus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Thalassolituus.
OX NCBI_TaxID=484498 {ECO:0000313|EMBL:SIS55897.1, ECO:0000313|Proteomes:UP000185639};
RN [1] {ECO:0000313|Proteomes:UP000185639}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24913 {ECO:0000313|Proteomes:UP000185639};
RA Varghese N., Submissions S.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FTOH01000002; SIS55897.1; -; Genomic_DNA.
DR RefSeq; WP_076514434.1; NZ_FTOH01000002.1.
DR AlphaFoldDB; A0A1N7K2X6; -.
DR STRING; 484498.SAMN05421686_102305; -.
DR Proteomes; UP000185639; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.450.350; CHASE domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR007895; MASE1.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF05231; MASE1; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM01079; CHASE; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50839; CHASE; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000313|EMBL:SIS55897.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000185639};
KW Transferase {ECO:0000313|EMBL:SIS55897.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 252..414
FT /note="CHASE"
FT /evidence="ECO:0000259|PROSITE:PS50839"
FT DOMAIN 540..758
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 779..894
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 829
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 898 AA; 98799 MW; CFFCB9347F4AA5E8 CRC64;
MFFVRIFIAA LAYFVFARLG TALAIPPDYA AAVWPAAGVA LASFLLFSRT VAFAGVLTGA
VLANLYTTTS ALNELSVTTL VSGVAMGVGA TLQGLFGAWL YRTYLPGRSR WDELSHLIRF
CFVVVALGSV VSTTIGNITL YVNEFIVTER LAFNWITWWA GDAIGALLVT PVIMVLAAPE
QIYSRDRKIK VMVPILLILT AVFGLFYKSV GFNRERIVSD LQASADELSQ LVDARLTISE
NKLIAYAALF SASEFVTPEE FALFSKRVMA RDDAFFGVGW TEVVDNSGRA RWETFYRERG
IDGFTFTELA EGGRLIEASH QDAYYPVLYI YPFEPNRRAF GLNLGANAER KAALDKAAIE
HVPVATAPIV LAQETGKKRA IILYMPVFDL EDDEALVGYS SGVLKVSGIL GESVFQSRQS
GLYFNLYDVT EGERLTIYEA AEQAHSNLPM HSYDAYFGTR KYHLEIFPAE NYVYGRNDWT
SYVILTGGFV IATLFLVFVL TTTGQIETVR RQVELRTAEL SDAVSRANAA SDAKSAFLAN
MSHELRTPLN AINGFLKLVL DTALTPVQKN YLQKADLASV TLLGLINQTL NYAKIESGNM
ELEQSSVRMR RIARKMEALF GHIADESALD FRIKLANDVP EVLIGDELRI EQITLNLLSN
AFKFTREGHI DLNISYEADD EKLQIRVTDS GVGIPADKME HIFAAFGQAD ASISRRYGGS
GLGLSISRRI AIMMKGDILV RSTEGQGSEF LVYLHLPVGD AAADDVGAPE SRGQLQGKCA
LIVEDIKVNQ MIVQEFLSKH GISTLIAENG REAVDQMSAR PAVDFILMDV QMPVMDGYTA
TREIRKLMPE IPIIGMTANA MDDDKMACLA AGMNDHIAKP IDPESLIRCV QDAVSKCG
//
