ID   A0A1N7KA18_9RHOB        Unreviewed;      1173 AA.
AC   A0A1N7KA18;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Multidrug efflux pump subunit AcrB {ECO:0000313|EMBL:SIS58446.1};
GN   ORFNames=SAMN05421795_101749 {ECO:0000313|EMBL:SIS58446.1};
OS   Phaeovulum vinaykumarii.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Phaeovulum.
OX   NCBI_TaxID=407234 {ECO:0000313|EMBL:SIS58446.1, ECO:0000313|Proteomes:UP000186098};
RN   [1] {ECO:0000313|Proteomes:UP000186098}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18714 {ECO:0000313|Proteomes:UP000186098};
RA   Varghese N., Submissions S.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FTOM01000001; SIS58446.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1N7KA18; -.
DR   STRING; 407234.SAMN05421795_101749; -.
DR   Proteomes; UP000186098; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF33; RND SUPERFAMILY EFFLUX PUMP PERMEASE COMPONENT; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186098};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        76..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        388..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        416..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        442..463
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        488..508
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        520..539
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        933..953
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        960..979
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        985..1009
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1030..1049
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1061..1086
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1106..1126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1138..1160
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1173 AA;  126234 MW;  A72AB528B036AF95 CRC64;
     MTDTPPTPDP ENTGRENNGP ENNGATPNLP ARRPEDLPRL ADRPAAQAAD SPADYTRAPE
     PGRTAGLVSL FTRHKTLANI LLVVILVAGL AAMPRLRAQF FPDMAVDEIS VSVIWEGASP
     EDVDRAIVQV LEPSLLVVEG VESSSSRASE GRAVISLEFE PGWDMGRAVD EVETAVAQAE
     DLPEEAEDPE VTRGAWRDTV TDLVLTGPMA LDQLGQLADE LVARLYAEGV TRTTIQGFAA
     PQVVVEVPSE NLVRHDLTLR EIAAVIGAEA ATAPAGDVAS GGARVRTGEE RRKVAEIAGL
     VLRAEPDGSL LTLGDVAQIR REGADRNRAY FVGDDPAVSI NVSRSAQGDA IGLQQKVEKV
     VAEMQATLPA SVTIELTRTR AEMIGQRLSL LLENGAMGLG LVLVLLFLFL NARTAFWVAM
     GIPVAMMAAI AMMYMGGLTL NVISIFALII TLGIVVDDAI VVGEHADFRA RHLREPPLLA
     AENGALRMLA PVFASTLTTI IAFAGLVIIG GRMGDMIRDI PLTVIAVLAA SLVECFLILP
     NHMVHALGKV GHGAWYDLPS QKVNEGFEWL RVKVMRPFTR FVIRARYPVL AMAGCILAWQ
     VSWVISGKVQ WRFFNPPEQG SMSANFSMLP GASREDTFEM MRALQASVET LGQEMEDKHG
     VNPILFMIGQ VGGNSGRGLA GADTKDQDLL GSVSIELIDA DLRPYSSMEF AGRLQAAAPR
     HPLLEEISMR AYRSGGTDAA ISVDLSGAEA RELKSAAEAL KAELARYPEV SAIEDNLAFD
     KAEMVLDLTA QGEALGFTLE ALARDLRARM AGIEAATFPD GPRSASIRVE LPPEDLRADF
     TERLYLRSPS GNWVPLSDIV SVRMQDGFSS IRREDGLRVV QVTAELSEDN ARRATEIMRS
     LREEILPRIA EQNGIAWTMT GMAEQERDFM SDALLGLVLC LLGIYIVLSW IFASWTRPMV
     VMSVIPFGLV GAIWGHWFWD LPLSMFAVVG LIGMSGIIIN DSIVLVTTVD QHARRHGLHQ
     AIVEAVSERL RPVFLTTATT VLGLAPILYE RSNAATFLKP TVITLVYGLG FGLIIVLCIV
     PAILAVQMDA GRQIRAFQRG LRVPGLRLAF GTAALALAGA FALTLGRAMA TGAELLPALA
     TYAGLVVVIV ALAGLAAPVL RRRARTGATL PAE
//