ID A0A1N7KFQ5_9FLAO Unreviewed; 1436 AA.
AC A0A1N7KFQ5;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Cobalt-zinc-cadmium resistance protein CzcA {ECO:0000313|EMBL:SIS60421.1};
GN ORFNames=SAMN05421796_101520 {ECO:0000313|EMBL:SIS60421.1};
OS Chryseobacterium piscicola.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=551459 {ECO:0000313|EMBL:SIS60421.1, ECO:0000313|Proteomes:UP000186246};
RN [1] {ECO:0000313|Proteomes:UP000186246}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21068 {ECO:0000313|Proteomes:UP000186246};
RA Varghese N., Submissions S.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC family. {ECO:0000256|ARBA:ARBA00007613}.
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DR EMBL; FTOJ01000001; SIS60421.1; -; Genomic_DNA.
DR STRING; 551459.SAMN05421796_101520; -.
DR Proteomes; UP000186246; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004763; CusA-like.
DR InterPro; IPR003423; OMP_efflux.
DR NCBIfam; TIGR00914; 2A0601; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF24; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR Pfam; PF00873; ACR_tran; 1.
DR Pfam; PF02321; OEP; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 327..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 517..536
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 855..874
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 881..900
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 906..931
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 952..973
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 985..1009
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1021..1038
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1436 AA; 159758 MW; 097303636A2EC6A3 CRC64;
MTLLLIIWGS WSATRLPIDA VPDITNNQVQ IITVCPTLAG QEVEQLVTFP IEQSIATVPD
IEETRSISRF GLSVITVVFK DKVDIYFARQ LINERLKQAE ENIPKGIGTP ELAPVSTGLG
EVYQYILHPK KGSEKKYNAK DLRAMQDWIV SRQLYGTEGV AEINGFGGEL KQYEVAVNPN
RLKAMGISVS DIFIALEKNN QNTGGAYIDK KPNAYFIRGI GLATSLEDIK NISVKNSGNI
PVFVKDVADV RFGHATRYGA MTYNGQTDAV GGVVMMLKDA NSNDVVNKIK EKIPTIQKSL
PADIIIEPFL DRTDLVDRAI STVEKNLIEG ALIVIFVLVV FLGNFRAGLI VASAIPLSLL
FALGMMNVFG VSANLMSLGA IDFGLIVDGA VIIVEATLHH LGLRKSVQRL TQSEMDEEVF
LSASKIRGSA AFGEIIILIV YIPILTLVGI EGKMFSPMAK TVGFAILGAL ILSLTYIPMM
CALFLSKKTI HKINFSDKMM ICLQKIYQPL LQKAIKIKYI IVGLTVVLFS ISAFIFSRMG
GEFIPQLQEG DFAFHCILPQ GSSLSQSIET SMQASRVIKQ LDEVKMVVGK TGSAEVPTDP
MPPEATDLII VLKPQKEWKS KKSYTELSDE IIEKLKVIPG VFFEANQPIQ MRFNELMTGI
REDVAVKIFG ENMDTLSIYA DKVSKVIQNV EGATSPQVER VGGLPQINVT YDRTRIANYG
LNVEDVNNVL STAFAGKIAG QIFENERRFD LVVRLDSLYR TDIDDVSNLM VPTNTGTQVP
LSQVANIEYK LGPSQISREV GKRRIVVGFN VKGRDIESVV KDIQQKLGKE IKLPSGYYFT
YGGQFENLKE ASQRLMIAVP VSLLLIFMLL YFTFHSFKQA TLIFTAIPMS AIGGVFALLL
RGMPFSISAG IGFIALFGVA VLNGIVLIGT FNQLEKDGVT DVFKRVIEGT KTRLRPVLMT
ATVASFGFLP MAISTSAGAE VQKPLATVVI GGLLTATFLT LFVLPMLYII FNSKINLTDK
LLKKPLTVII LIGTLFLSQN LKAQSSREIS LDQAIELLQE NNPSMKAKDL NIQSSEALIP
TAKEIPKLDF SAQLGQYNSP KFDQSFAISQ TIPFPTLFKA RKELIQEEIK TKKIEKQVTE
NELIKQVRSY FYQIEYLQYN QSKLQYLDSL YGDFIRIATV RFRAGDIKKI EINTAETQKG
EISLLFQQNK VHLNNAYKNL KTLLNTDEDI SIPDSQKYEP LKVEYLLDSA TVENHPSIQI
FKQNMEVLEK NKNVEKAQGL PDFSIGYTNQ SLIGFHTLNG QEKYYGSENR FNAVTVGVAI
PLTFGAAKAR MKSLEYQKQM EEKNAKFQMQ QLDAQLENSF NQYQQDVQQY QYYLNQAIPN
AKSIVKAAQL GYKTGEISYV EYLFALQTAT NIELKYLQSI QQVNQTVINI NSLINK
//
