ID A0A1N7KHP9_9GAMM Unreviewed; 704 AA.
AC A0A1N7KHP9;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05421760_102455 {ECO:0000313|EMBL:SIS61128.1};
OS Neptunomonas antarctica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Neptunomonas.
OX NCBI_TaxID=619304 {ECO:0000313|EMBL:SIS61128.1, ECO:0000313|Proteomes:UP000185999};
RN [1] {ECO:0000313|Proteomes:UP000185999}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22306 {ECO:0000313|Proteomes:UP000185999};
RA Varghese N., Submissions S.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FTOE01000002; SIS61128.1; -; Genomic_DNA.
DR RefSeq; WP_054343376.1; NZ_LJSI01000054.1.
DR AlphaFoldDB; A0A1N7KHP9; -.
DR STRING; 619304.SAMN05421760_102455; -.
DR OrthoDB; 1931120at2; -.
DR Proteomes; UP000185999; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.250.3020; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR017055; Sig_transdc_His_kinase_DctB.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PIRSF; PIRSF036431; STHK_DctB; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 322..367
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 486..698
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 704 AA; 78846 MW; F629ED2C43E7F4A5 CRC64;
MLVKRSIIVV VMAAIFSLIL SWQSYIYTRD WEVTQLHQQG SSKLLDTISA LRVAIDQYRY
LPFLLSQNRD VKDLLIRPNP DKIVRVSRYL EQTNLVAGSA ALMVLDRTGR VVAYSNWREQ
DANTAQSYQD APFFKQATAG EQGRYFVVDG KPASPSYYLS AAIYSRQQFI GVSVMRLDIE
KVKEQLSLEY AFYVADKEGQ LLFASQSLLT GQAFLTNKSL LNGGDNFWPL APLYTENLND
GRKISLWKPG GGAQLNLSVI LDDLGWNVGI LAPIESAQQK AFYVSSIVAG GCLALALLVL
YLREFRLKRR SQADVIRAQR DSEQRQRYII NTAQVGLITV DKNGAIVFIN PMVMQQFGVS
LALIINQPLH IIFADIDQFT PLKRWLDGLS QGEFTPITGY EVVGKRSDGS VFPILFSIRM
MTATPEPSYL VTMIDITRRK RLEHTLREVN ESLEHKVVER TQALQSAQSE LVQAEKLAAL
GRMSTAIVHE LNQPLTAMRN YLAIIRRVMD RPELLNENLI LVNSLVDRMA LITGQLKTFA
YKNPDKRGSS ELIHAINHVL GQFDGVFSEH HIRCQFTHEL PCYWVDADEV RVEQVLINLV
KNACDAMQGC TGLRDVSIRV NQLNEQIVLE ISDSGEGATD AQLAHMFEPF YTTKTMGSGL
GLGLPIVEGI IRDLGGKIKV GRNQACGLCF TVYLPLSAVE EGES
//
