ID   A0A1N7KS91_9RHOB        Unreviewed;       306 AA.
AC   A0A1N7KS91;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=inorganic diphosphatase {ECO:0000256|ARBA:ARBA00012146};
DE            EC=3.6.1.1 {ECO:0000256|ARBA:ARBA00012146};
DE   AltName: Full=Pyrophosphate phospho-hydrolase {ECO:0000256|ARBA:ARBA00032535};
GN   ORFNames=SAMN05421580_10316 {ECO:0000313|EMBL:SIS64417.1};
OS   Rhodobacter aestuarii.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Rhodobacter.
OX   NCBI_TaxID=453582 {ECO:0000313|EMBL:SIS64417.1, ECO:0000313|Proteomes:UP000186221};
RN   [1] {ECO:0000313|Proteomes:UP000186221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19945 {ECO:0000313|Proteomes:UP000186221};
RA   Varghese N., Submissions S.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=diphosphate + H2O = H(+) + 2 phosphate; Xref=Rhea:RHEA:24576,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:43474; EC=3.6.1.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00000926};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|ARBA:ARBA00001936};
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DR   EMBL; FTOG01000003; SIS64417.1; -; Genomic_DNA.
DR   RefSeq; WP_076484043.1; NZ_QAXT01000004.1.
DR   AlphaFoldDB; A0A1N7KS91; -.
DR   STRING; 453582.SAMN05421580_10316; -.
DR   OrthoDB; 9766150at2; -.
DR   Proteomes; UP000186221; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0004427; F:inorganic diphosphate phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.310.20; DHHA2 domain; 1.
DR   Gene3D; 3.90.1640.10; inorganic pyrophosphatase (n-terminal core); 1.
DR   InterPro; IPR001667; DDH_dom.
DR   InterPro; IPR038763; DHH_sf.
DR   InterPro; IPR004097; DHHA2.
DR   InterPro; IPR038222; DHHA2_dom_sf.
DR   PANTHER; PTHR12112; BNIP - RELATED; 1.
DR   PANTHER; PTHR12112:SF22; MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE; 1.
DR   Pfam; PF01368; DHH; 1.
DR   Pfam; PF02833; DHHA2; 1.
DR   SMART; SM01131; DHHA2; 1.
DR   SUPFAM; SSF64182; DHH phosphoesterases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Manganese {ECO:0000256|ARBA:ARBA00023211};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186221}.
FT   DOMAIN          181..304
FT                   /note="DHHA2"
FT                   /evidence="ECO:0000259|SMART:SM01131"
SQ   SEQUENCE   306 AA;  32620 MW;  262BC0BDF6BE3E9B CRC64;
     MTTKVFGHKS PDTDSTGSPI AWAWYMSEVL ATPATPVLLG EPNTEAAFVL EHWNLSKPEI
     ISDVAEGEKV VIVDTNNPAE LPAGINKADI TAIIDHHKLV GGLETKGPID ITIRPLACTA
     TIMYDLMGGA IAKAPRGIKG AMLSCILSDT LEFRSPTTTE HDKAVAEALA ADLGVNMGEL
     AAAMFEAKSD VSAFSDAELL RMDSKEYTVD GKELRVSVLE TTAPKLLLDR KDSLMASMVD
     VAKEDGADQV LLFIIDILNE EATLLVPNDF VKAVAEASFG CTVSGDTLVL PGIMSRKKQI
     IPALKV
//