ID A0A1N7PSI3_9RHOB Unreviewed; 308 AA.
AC A0A1N7PSI3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:SIT13584.1};
GN ORFNames=SAMN05421774_106101 {ECO:0000313|EMBL:SIT13584.1};
OS Gemmobacter megaterium.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Gemmobacter.
OX NCBI_TaxID=1086013 {ECO:0000313|EMBL:SIT13584.1, ECO:0000313|Proteomes:UP000186141};
RN [1] {ECO:0000313|EMBL:SIT13584.1, ECO:0000313|Proteomes:UP000186141}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26375 {ECO:0000313|EMBL:SIT13584.1,
RC ECO:0000313|Proteomes:UP000186141};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FTOT01000006; SIT13584.1; -; Genomic_DNA.
DR RefSeq; WP_076532567.1; NZ_FTOT01000006.1.
DR AlphaFoldDB; A0A1N7PSI3; -.
DR STRING; 1086013.SAMN05421774_106101; -.
DR OrthoDB; 9803287at2; -.
DR Proteomes; UP000186141; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR48075:SF1; LAMBDA-CRYSTALLIN HOMOLOG; 1.
DR Pfam; PF00725; 3HCDH; 1.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186141};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..308
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012636677"
FT DOMAIN 6..180
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 184..251
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 308 AA; 33030 MW; B58D3510AF91D718 CRC64;
MMFTRTAVLG AGTIGASWAA LFAATGREVT VYDPASDAEA RVARMIETAA EPLAALGWDN
AGDLSRIRYT ADPADAVVGA TFIQESVPER LDIKHDLYAR IEPVLEPGAI IGSSTSGLTL
GQMQAGFTSP GRLVLAHPFN PPHLIPLVEL MANERTDADV LDSAQRFYES IGKVCIRLNK
EVPGHVANRL QAALWREAIH LAAEGVASVG DIDRAIAHGP GLRWAIMGPS MLFHLAGGDN
GMRGLCAHLG PAFEAWWADL GAAHLTPEVV EMLVQGVESE AEGQSLSELA RRRDRLLLGY
LRARTEQI
//
