ID A0A1N7RR15_9BURK Unreviewed; 807 AA.
AC A0A1N7RR15;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Glycine cleavage T-protein (Aminomethyl transferase) {ECO:0000313|EMBL:SIT37548.1};
GN ORFNames=BN2475_120087 {ECO:0000313|EMBL:SIT37548.1};
OS Paraburkholderia ribeironis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=1247936 {ECO:0000313|EMBL:SIT37548.1, ECO:0000313|Proteomes:UP000187012};
RN [1] {ECO:0000313|EMBL:SIT37548.1, ECO:0000313|Proteomes:UP000187012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=STM7296 {ECO:0000313|EMBL:SIT37548.1,
RC ECO:0000313|Proteomes:UP000187012};
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; CYGX02000012; SIT37548.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1N7RR15; -.
DR STRING; 1247936.BN2475_120087; -.
DR OrthoDB; 9806257at2; -.
DR Proteomes; UP000187012; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000187012};
KW Transferase {ECO:0000313|EMBL:SIT37548.1}.
FT DOMAIN 7..365
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 368..420
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 423..693
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 720..799
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 807 AA; 88913 MW; 50E8AD49618E5394 CRC64;
MKSHCQVAVI GGGVVGASVL YHLTRFGWKD VVLLERKVLT AGSTWHAAAG FHAFNGDPNI
VRLQEYTISL YKEIQEIGDQ DVGLHVPGGI TIAATPERWE FLRTEASRHR FMGLETELIT
PAEIAAKCPL VDVSDVKGGL WAPNEGHLDP YGCTQAYARA ARRQGAEIYQ HTCVEALRQC
PDGSWIVTTD KGEIHAEHVV NAAGLWAREV GAMAGVKLPL IPMEHHYLVT EDIPELVQLG
RQIPVMVDLD GEIYLRQEHH GVLFGVYERS STPWALGGTP WEYGETDLLP PRLERIEEEL
MHGFQRFPSV GNAGIKRVVN GPFTFTPDGN PLVGPVRGLR NYWAACGCMA GFSQGGGVGL
ALAQWMIEGE PHDNVFGMDV ARFPDLTQTY VTAKAQEFYE HRFYLARPNE QWPAGRPMKT
TPLYDLQKEA NAVFGVMYGL ESPMWFAPPG TPAEETPSFR RSNAFETVAR ECRAVREAVG
VFDACGYAKY EVSGSGAAAW LDRVFASRLP ELGRARLAPL LSESGRLKGD LTLLRLAEDR
FLITGSGYLQ EWHQRWFGGL LPADGSVRID NRSDSLAMLV VAGPRSRELM RDLFGADSAV
STQRFMQVVQ GDADVAPAWV ARLSLSGELA YEIYVDAPYV RSVYAKLLSL GEAYGLRPYG
VWALLSLRIE KGFGIWSREF GPEYTPSMAD LERFIAYDKG DFIGRDAALA QRGVTPEQCL
VTFDVDALDA DAAGFEPVWV GDQVAGYTTS GAYGHSTGKS LAMAYVKSAW LEGGADHPFE
IQILGERRAA RLLREPAYDP AGARMRM
//
