ID A0A1N7SS77_9BURK Unreviewed; 579 AA.
AC A0A1N7SS77;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Pseudomonalisin {ECO:0000313|EMBL:SIT49786.1};
DE EC=3.4.21.100 {ECO:0000313|EMBL:SIT49786.1};
GN Name=pcp {ECO:0000313|EMBL:SIT49786.1};
GN ORFNames=BN2475_1790002 {ECO:0000313|EMBL:SIT49786.1};
OS Paraburkholderia ribeironis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=1247936 {ECO:0000313|EMBL:SIT49786.1, ECO:0000313|Proteomes:UP000187012};
RN [1] {ECO:0000313|EMBL:SIT49786.1, ECO:0000313|Proteomes:UP000187012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=STM7296 {ECO:0000313|EMBL:SIT49786.1,
RC ECO:0000313|Proteomes:UP000187012};
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|PROSITE-ProRule:PRU01032};
CC Note=Binds 1 Ca(2+) ion per subunit. {ECO:0000256|PROSITE-
CC ProRule:PRU01032};
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DR EMBL; CYGX02000179; SIT49786.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1N7SS77; -.
DR STRING; 1247936.BN2475_1790002; -.
DR OrthoDB; 5481934at2; -.
DR Proteomes; UP000187012; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd04056; Peptidases_S53; 1.
DR CDD; cd11377; Pro-peptidase_S53; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015366; S53_propep.
DR InterPro; IPR030400; Sedolisin_dom.
DR PANTHER; PTHR14218:SF42; PEPTIDASE S53 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR14218; PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF09286; Pro-kuma_activ; 1.
DR SMART; SM00944; Pro-kuma_activ; 1.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51695; SEDOLISIN; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU01032};
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU01032,
KW ECO:0000313|EMBL:SIT49786.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU01032}; Protease {ECO:0000256|PROSITE-ProRule:PRU01032};
KW Reference proteome {ECO:0000313|Proteomes:UP000187012};
KW Serine protease {ECO:0000256|PROSITE-ProRule:PRU01032};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..579
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013292336"
FT DOMAIN 218..577
FT /note="Peptidase S53"
FT /evidence="ECO:0000259|PROSITE:PS51695"
FT ACT_SITE 293
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01032"
FT ACT_SITE 297
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01032"
FT ACT_SITE 495
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01032"
FT BINDING 537
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01032"
FT BINDING 538
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01032"
FT BINDING 555
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01032"
FT BINDING 557
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01032"
SQ SEQUENCE 579 AA; 61153 MW; E89579A06E9DA6DC CRC64;
MKRNYRLALP LPSPRRLACA VPLVFSAAAA HATTDWVDTH TNAFLTGPQL MARNAAPSLE
LADGEITDIV VSLNLRNAAQ LEQLGHDVNQ PGNAHYRQYL TPEQFLVSYA PTEAQVKSVV
DYLRKSGFVN VEVAPNRLLV SARGTAGTVK TAFNTSLVHY QDASRSGFMN ASKAQVPRAL
GDAVGSVLGL QNIARAQPML RIGNVEKPQA LAAGTATGHY PKEFPGLYNA TGVPTAAGVT
VGIITMGGVS QTLKDLEQFT SSNGYGTVTT QTEKTNGTGT TGSYSDNPFL QSEWDLDSQS
IVGSAGGQVG KLIFYMADQN AAGDTGLTQA FNRAVWDNTA KVINVSLGWC ETDADKDGTI
DAQEQIFTTA AAQGQTFSVS SGDEGAYECN NRGFPDGTNY TVSWPAASPH VLAIGGTTLY
TTSTGAFSNE TVWNEGLDPT GKLWATGGGV STILPAPVWQ SGSNRRLPDV SFDAALSTGA
YIYNYGQLQQ VGGTSLAAPI FTGFWARLLA ANGTSLGFPA GDLYRAIPSN PSLVRYDVVS
GNNGYQGLGY KAGTGWDYPT GFGSLSITNL NELIRSGRF
//
