ID A0A1P6BSD7_BRUMA Unreviewed; 397 AA.
AC A0A1P6BSD7;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 22-FEB-2023, entry version 24.
DE SubName: Full=BMA-ACL-12, isoform b {ECO:0000313|EMBL:CDP91598.1, ECO:0000313|WBParaSite:Bm1873a.1};
GN Name=bma-acl-12 {ECO:0000313|WormBase:Bm1873b};
GN Synonyms=Bma-acl-12 {ECO:0000313|EMBL:CDP91598.1};
GN ORFNames=Bm1873 {ECO:0000313|WormBase:Bm1873b}, BM_Bm1873
GN {ECO:0000313|EMBL:CDP91598.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CDP91598.1};
RN [1] {ECO:0000313|EMBL:CDP91598.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP91598.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CDP91598.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP91598.1};
RG WormBase Consortium;
RA Ghedin E., Paulini M.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm1873a.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2022) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 1-acyl-sn-glycerol-3-phosphate
CC acyltransferase family. {ECO:0000256|ARBA:ARBA00008655}.
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DR EMBL; LN856451; CDP91598.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1P6BSD7; -.
DR EnsemblMetazoa; Bm1873a.1; Bm1873a.1; WBGene00222134.
DR WBParaSite; Bm1873a.1; Bm1873a.1; WBGene00222134.
DR WormBase; Bm1873b; BM47133; WBGene00222134; Bma-acl-12.
DR OrthoDB; 2875588at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd07990; LPLAT_LCLAT1-like; 1.
DR InterPro; IPR032098; Acyltransf_C.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR10983:SF14; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE ACL-12-RELATED; 1.
DR PANTHER; PTHR10983; 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED; 1.
DR Pfam; PF16076; Acyltransf_C; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006672};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 117..241
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 397 AA; 45850 MW; 082B265AE4774323 CRC64;
MLQTGDARIG LDGPTVTAED GFLTKVMISS MDVRKVIALI GAFYWTIMTV FVVPGIITAT
FLTVMIPVLC ISVSWFNWLD HKLCRMVNGH WSSAIQIAGI NIVEYGDDIS KLSEKRVLFL
ANHLGLADHF VIMSALRNKG TVVEKYLWVI YNIWKMTPLG VMWMIHGNYF VDGGVAKRDQ
MIEDFKTHLK RNYWKYDHRW IIMYPEGARL YRIKESNARY AAREGYKIFR HCALPRTGAA
HATIETTTTA NYATVEDTGD SLEYIIDCTL GYQNGDVPSI GNWLFGDLPN GIPNVAVHYK
IYRIRPEWKD ENMLRHWLYD IYEKKDELLE KYYESGVFPM DSQHHPTVVR NSISSCLFVE
AFWLLLLYLH YSIWLKSFAS LIYRCIVVIS LTFLGIF
//
