ID A0A1P6BXR7_BRUMA Unreviewed; 1100 AA.
AC A0A1P6BXR7;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=BMA-SCC-3, isoform c {ECO:0000313|EMBL:CDP98716.1};
DE SubName: Full=SCD domain-containing protein {ECO:0000313|WBParaSite:Bm3437a.1};
GN Name=Bma-scc-3 {ECO:0000313|EMBL:CDP98716.1,
GN ECO:0000313|WBParaSite:Bm3437a.1};
GN ORFNames=BM_Bm3437 {ECO:0000313|EMBL:CDP98716.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|Proteomes:UP000006672, ECO:0000313|WBParaSite:Bm3437a.1};
RN [1] {ECO:0000313|EMBL:CDP98716.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP98716.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CDP98716.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP98716.1};
RG WormBase Consortium;
RA Ghedin E., Paulini M.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm3437a.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SCC3 family.
CC {ECO:0000256|ARBA:ARBA00005486}.
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DR EMBL; LN856998; CDP98716.1; -; Genomic_DNA.
DR STRING; 6279.A0A1P6BXR7; -.
DR EnsemblMetazoa; Bm3437a.1; Bm3437a.1; WBGene00223698.
DR WBParaSite; Bm3437a.1; Bm3437a.1; WBGene00223698.
DR OMA; VQHYVFS; -.
DR OrthoDB; 5354237at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProt.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:UniProt.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR039662; Cohesin_Scc3/SA.
DR InterPro; IPR020839; SCD.
DR InterPro; IPR013721; STAG.
DR PANTHER; PTHR11199:SF0; LD34181P-RELATED; 1.
DR PANTHER; PTHR11199; STROMAL ANTIGEN; 1.
DR Pfam; PF21581; SCD; 1.
DR Pfam; PF08514; STAG; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51425; SCD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006672}.
FT DOMAIN 331..416
FT /note="SCD"
FT /evidence="ECO:0000259|PROSITE:PS51425"
FT REGION 1..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1076..1100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1100 AA; 125471 MW; 448D629BBC9083DB CRC64;
MEEEGQDAYR MTTRGITRHY VDSPVSGHVD STHSSMSLSH ISSEDEQQHS EFHLESSTDS
LFRTPSLTTR GRKRRSYEEG VAVSIESPTI SRRGRPRGST RPRGVGRRAS GTYSQEDADE
SSLFSMVKSG KNLHTVIDNW IEEYERHPDN ALVQLQQFFI SCCGCKGIIS SVMLQTMEYS
EIIRQMTDQF DEDTGDYPLV MPGPLWKRFK QTLADFILLL VNKCKSSYVF DQRLMDSVIQ
LLTGLADSQV RAFRHTSTFI AMKLSSALVD VALELVDLKA KNIRQVETEK AKLKAEGPNS
RLDVLINKKA EIDDKTEDIR QMLTYIFKSV FVHRYRDVVP DIRSICINEL GQWMSVYPDH
FLEDSYLKYI GWSLYDKMSD VRLKCILALL PLYSQPHMAQ KLELFTNKFK DRLVTMVMDK
DSDVAVRACQ LLTEIYRIYP AALTLKDCVP IYEMVYCNHR GLAQAAGEFL NTKVFQNLQV
LAPEKNRASD SAKQLIIDLV QFFVEGDCHD HAAYLVDALI DTNPMIKDWK TMSDLLLSGE
AEGFESELIE VLVCSVKQAA SGESPIGRAH LSRKGLVVNK DVRLLQEDRA RLSEVLIPQL
PQLLQRFIAD RDKVANLITV PLHFQLDMYM ASRLEKHLDE LMSILESIVE KHADDEILQC
VAEIMSYFTT NVAVAQHTET HHLKMLDGLA LQLRHSIQHF HREQTVDEED DAAMLAAFRK
ITAFAMFEDL KKWQLWDVAL SVLTNADDKQ VSRDVGEKAV ILLFATLSWD INRLVTEQEP
NKAEAIKKLR KHRDQFTALV TSIMMSGASG VENAFLCFVD ALMMFNGLPD KSLSIELNRD
ITRALSMFVE DNVFVEENDA ERSLDQQTQV ELMHKRRKIL VQFCKLILHG ILPIYEACIV
LQFYTKFYTD FGDILKTLLT KCRDMDRLSC ARAVATALCH YYEEIKRASE GNCIDPNSDD
FASIRDLAKR FSNLFGSDPV KSREALAIIH KDGIVFALRN DESINRDMPH TNLSFLEILC
EFSSRLLRQD KISVLRYLER HGEMYAKEEP YIIYKASLQE RSDDVSTVRN LALRGRSRGR
GRGKGTPTYT PAASVYGGDD
//
