ID A0A1P8AMI8_ARATH Unreviewed; 753 AA.
AC A0A1P8AMI8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
GN Name=ARK2 {ECO:0000313|EMBL:ANM57838.1, ECO:0000313|TAIR:AT1G01950};
GN Synonyms=armadillo repeat kinesin 2 {ECO:0000313|EMBL:ANM57838.1},
GN AtKINUb {ECO:0000313|EMBL:ANM57838.1}, gene B
GN {ECO:0000313|EMBL:ANM57838.1};
GN OrderedLocusNames=At1g01950 {ECO:0000313|Araport:AT1G01950,
GN ECO:0000313|EMBL:ANM57838.1};
GN ORFNames=F22M8.8 {ECO:0000313|EMBL:ANM57838.1}, F22M8_8
GN {ECO:0000313|EMBL:ANM57838.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:ANM57838.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:ANM57838.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. Ungrouped subfamily.
CC {ECO:0000256|ARBA:ARBA00010103}.
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DR EMBL; CP002684; ANM57838.1; -; Genomic_DNA.
DR RefSeq; NP_001320318.1; NM_001331317.1.
DR AlphaFoldDB; A0A1P8AMI8; -.
DR SMR; A0A1P8AMI8; -.
DR ProteomicsDB; 214091; -.
DR EnsemblPlants; AT1G01950.4; AT1G01950.4; AT1G01950.
DR GeneID; 839306; -.
DR Gramene; AT1G01950.4; AT1G01950.4; AT1G01950.
DR Araport; AT1G01950; -.
DR TAIR; AT1G01950; ARK2.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; A0A1P8AMI8; baseline and differential.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR047149; KIF11-like.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47970:SF31; ARMADILLO REPEAT-CONTAINING KINESIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR47970; KINESIN-LIKE PROTEIN KIF11; 1.
DR Pfam; PF00514; Arm; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00185; ARM; 4.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50176; ARM_REPEAT; 2.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 1: Evidence at protein level;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Microtubule {ECO:0000256|RuleBase:RU000394};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A1P8AMI8,
KW ECO:0007829|ProteomicsDB:A0A1P8AMI8};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..261
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REPEAT 495..537
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 536..579
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 389..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 457..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 4..11
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 753 AA; 83213 MW; 4F5676C815EC527D CRC64;
MAYGQTGTGK TFTLGRLGDE DTAARGIMVR SMEDIIGGTS LDTDSISVSY LQLYMETIQD
LLDPTNDNIA IVEDPRTGDV SLPGATHVEI RNQQNFLELL QLGETHRVAA NTKLNTESSR
SHAILMVHVK RSVVENEFPV SNEMESSSHF VRPSKPLVRR SKLVLVDLAG SERVHKSGSE
GHMLEEAKSI NLSLSALGKC INAIAENSPH VPLRDSKLTR LLRDSFGGTA RTSLIVTIGP
SPRHRGETTS TILFGQRAMK VENMLKIKEE FDYKSLSKKL EVQLDKVIAE NERQLKAFDD
DVERINRQAQ NRISEVEKNF AEALEKEKLK CQMEYMESVK KLEEKLISNQ RNHENGKRNG
EVNGVVTASE FTRLKESLEN EMKLRKSAEE EVSKVKSQST LKTRSGEGED AGITRLQKLL
EDEALQKKKL EEEVTILRSQ LVQLTFEADQ MRRCLDRGAP GNSYSGTDSL PSRHSQARES
VNGQKAPFAT LCEQVGLQKI LQLLESDDAN IRIHAVKVVA NLAAEEANQE KIVEAGGLTS
LLMLLRSYED ETVRRVAAGA IANLAMNEVS QQLIVDQGGI SLLSLTAADA EDPQTLRMVA
GAIANLCGND KLQARLWSDG GIKALLGMVR CGHPDVLAQV ARGIANFAKC ESRATTQGVK
SGRSLLIEDG ALPWIVQHAN DEAAPIRRHI ELALCHLAQH EVNAKEMISG GALWELVRIS
KECSREDIRS LAHRTLSSSP VFRSEIRRLG IQF
//
