ID A0A1P8ASD8_ARATH Unreviewed; 443 AA.
AC A0A1P8ASD8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=DNA repair metallo-beta-lactamase family protein {ECO:0000313|EMBL:ANM59527.1};
GN OrderedLocusNames=At1g19025 {ECO:0000313|Araport:AT1G19025,
GN ECO:0000313|EMBL:ANM59527.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:ANM59527.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:ANM59527.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA repair metallo-beta-lactamase (DRMBL)
CC family. {ECO:0000256|ARBA:ARBA00010304}.
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DR EMBL; CP002684; ANM59527.1; -; Genomic_DNA.
DR RefSeq; NP_001321878.1; NM_001332382.1.
DR AlphaFoldDB; A0A1P8ASD8; -.
DR SMR; A0A1P8ASD8; -.
DR EnsemblPlants; AT1G19025.2; AT1G19025.2; AT1G19025.
DR GeneID; 838484; -.
DR Gramene; AT1G19025.2; AT1G19025.2; AT1G19025.
DR KEGG; ath:AT1G19025; -.
DR Araport; AT1G19025; -.
DR TAIR; AT1G19025; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; A0A1P8ASD8; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.12650; -; 1.
DR InterPro; IPR011084; DRMBL.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR23240; DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; 1.
DR PANTHER; PTHR23240:SF31; DNA REPAIR METALLO-BETA-LACTAMASE FAMILY PROTEIN; 1.
DR Pfam; PF07522; DRMBL; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548}.
FT DOMAIN 128..241
FT /note="DNA repair metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF07522"
SQ SEQUENCE 443 AA; 50234 MW; FF83D4C4C55F3C23 CRC64;
MFLFEGSFGN ILHTGDCRLT LDCLHSLPEK YVGRSHGMKP KCSLGYIFLD CTFGKSSHSQ
RFPTKHSAIR QIINCIWNHP DAPVVYLACD MLGQEDVLLE VSRTFGSKIY VDKATNLECF
RSLMVIVPEI VSEDPSSRFH IFSGFPKLYE RTSAKLAEAR SKLQSEPLII RPSAQWYVCD
DEDDWKSGSI QKQRKVRFSE AVKDEFGLWH VCYSMHSSRA ELESAMQLLS PKWVVSTVPS
CRAMELNYVK KNCFISRFSP DDPFWKLLDI DMEASPVAAA DTQTVALSCC LMSEQIILDS
GKSKLEPVIE SSSTKKKLLS LSPENSLPVT LFGRARQSSQ ECDQLHERKV IHTQCVYTKT
SPVLEKLNVK VVIEPLQDDT KEETVEKESC TIFSTSTSKE TCKDLSGDLR KLYRSMNAPV
PRPLPSLMEL MNARKRSRNH LSF
//
