ID A0A1P8ATL6_ARATH Unreviewed; 628 AA.
AC A0A1P8ATL6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=GDSL-like lipase/acylhydrolase superfamily protein {ECO:0000313|EMBL:ANM59976.1};
GN Name=RXW8 {ECO:0000313|EMBL:ANM59976.1, ECO:0000313|TAIR:AT1G58520};
GN OrderedLocusNames=At1g58520 {ECO:0000313|Araport:AT1G58520,
GN ECO:0000313|EMBL:ANM59976.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:ANM59976.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:ANM59976.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
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DR EMBL; CP002684; ANM59976.1; -; Genomic_DNA.
DR RefSeq; NP_001322291.1; NM_001333842.1.
DR AlphaFoldDB; A0A1P8ATL6; -.
DR SMR; A0A1P8ATL6; -.
DR ProteomicsDB; 203525; -.
DR EnsemblPlants; AT1G58520.5; AT1G58520.5; AT1G58520.
DR GeneID; 842218; -.
DR Gramene; AT1G58520.5; AT1G58520.5; AT1G58520.
DR Araport; AT1G58520; -.
DR TAIR; AT1G58520; RXW8.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; A0A1P8ATL6; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR PANTHER; PTHR13018:SF117; CSC1-LIKE PROTEIN RXW8; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A1P8ATL6,
KW ECO:0007829|ProteomicsDB:A0A1P8ATL6};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 442..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..504
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 510..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..226
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 237..503
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 574..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..605
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 628 AA; 71488 MW; BC718BB88F738385 CRC64;
MVHKEIHLES SEVFTIENLK EGSKWLWVHC LALYIITSAA CLLLYFEYST IAKMRLGHIT
GCASKPSQFT VLIRAIPWSP EQSYSDTLSK FFTNYYSSSY VSHQMVYHNG IIQRLLRDAE
RMCQTLKHVS PEINCKPSLR PCTFCGGPTA TSSFHILSNE ADSVKGMELG ELTMTTTTTE
QERSAAFVFF KTRYDALVVS EVLQSSNPML WVTDLAPEPH DVYWKNLNIP YRQLWIRKIA
TLVGAVAFMF VFLIPVTFIQ GLTQLVQLSH AFPFLRGILS KNFINQVITG YLPSVILILF
FYAVPPLMMY FSALEGCISR SIRKKSACIK VLYFTIWNVF FVNILSGSVI RQLNVFSSVR
DIPAQLARAV PTQAGFFMTY CFTSGWASLA CEIMQPMALI WNLVAKVVTK NEDESYETLR
FPYHTEIPRL LLFGLLGFTN SVIAPLILPF LLIYFFLAYL IYKNQILNVY ITKYESGGQY
WPIFHNTTIF SLILTQIIAL GFFGLKLSTV ASGFTIPLIL LTLLFSEYCR QRFAPIFNKN
PAQVLIDMDR ADEISGKMEE LHKKLHNVYS QIPLHSQKSS SKAECSNPFK KQELPDPEKL
KPEEGDAIAK ELWGFQGNES GQEHDTKS
//
