ID A0A1P8AV20_ARATH Unreviewed; 741 AA.
AC A0A1P8AV20;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Leucine-rich repeat protein kinase family protein {ECO:0000313|EMBL:ANM60486.1};
GN OrderedLocusNames=At1g51890 {ECO:0000313|Araport:AT1G51890,
GN ECO:0000313|EMBL:ANM60486.1};
GN ORFNames=T14L22.10 {ECO:0000313|EMBL:ANM60486.1}, T14L22_10
GN {ECO:0000313|EMBL:ANM60486.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:ANM60486.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:ANM60486.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
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DR EMBL; CP002684; ANM60486.1; -; Genomic_DNA.
DR RefSeq; NP_001322770.1; NM_001333517.1.
DR AlphaFoldDB; A0A1P8AV20; -.
DR SMR; A0A1P8AV20; -.
DR ProteomicsDB; 208025; -.
DR EnsemblPlants; AT1G51890.3; AT1G51890.3; AT1G51890.
DR GeneID; 841616; -.
DR Gramene; AT1G51890.3; AT1G51890.3; AT1G51890.
DR Araport; AT1G51890; -.
DR TAIR; AT1G51890; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; A0A1P8AV20; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR024788; Malectin-like_Carb-bd_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR45631; OS07G0107800 PROTEIN-RELATED; 1.
DR PANTHER; PTHR45631:SF82; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF12819; Malectin_like; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 1: Evidence at protein level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ANM60486.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A1P8AV20,
KW ECO:0007829|ProteomicsDB:A0A1P8AV20};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..741
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010176893"
FT TRANSMEM 498..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 570..741
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 597
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 741 AA; 83138 MW; 35E2CF392F40856E CRC64;
MRFLSFLIFV FAVLGLVQAQ DQSGFISLDC GLVPTEITYV EKSTNITYRS DATYIDSGVP
GKINEVYRTQ FQQQIWALRS FPEGQRNCYN FSLTAKRKYL IRGTFIYGNY DGLNQLPSFD
LYIGPNKWTS VSIPGVRNGS VSEMIHVLRQ DHLQICLVKT GETTPFISSL ELRPLNNNTY
VTKSGSLIVV ARLYFSPTPP FLRYDEDVHD RIWIPFLDNK NSLLSTELSV DTSNFYNVPQ
TVAKTAAVPL NATQPLKINW SLDDITSQSY IYMHFAEIEN LEANETREFN ITYNGGENWF
SYFRPPKFRI TTVYNPAAVS SLDGNFNFTF SMTGNSTHPP LINGLEIYQV LELPQLDTYQ
DEVSAMMNIK TIYGLSKRSS WQGDPCAPEL YRWEGLNCSY PNFAPPQIIS LNLSGSNLSG
TITSDISKLT HLRELDLSNN DLSGDIPFVF SDMKNLTLIN LSGNKNLNRS VPETLQKRID
NKSLTLIRDE TGKNSTNVVA IAASVASVFA VLVILAIVFV VIRKKQRTNE ASGPRSFTTG
TVKSDARSSS SSIITKERKF TYSEVLKMTK NFERVLGKGG FGTVYHGNLD DTQVAVKMLS
HSSAQGYKEF KAEVELLLRV HHRHLVGLVG YCDDGDNLAL IYEYMEKGDL RENMSGKHSV
NVLSWETRMQ IAVEAAQGLE YLHNGCRPPM VHRDVKPTNI LLNERSQAKL ADFGLSRSFP
VDGESHVMTV VAGTPGYLDP E
//
