ID A0A1P8B3M4_ARATH Unreviewed; 710 AA.
AC A0A1P8B3M4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Ankyrin repeat family protein {ECO:0000313|EMBL:ANM66193.1};
GN OrderedLocusNames=At4g03490 {ECO:0000313|Araport:AT4G03490,
GN ECO:0000313|EMBL:ANM66193.1};
GN ORFNames=F9H3.12 {ECO:0000313|EMBL:ANM66193.1}, F9H3_12
GN {ECO:0000313|EMBL:ANM66193.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:ANM66193.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:ANM66193.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=10617198; DOI=10.1038/47134;
RG EU;
RG CSHL and WU Arabidopsis Sequencing Project;
RA Mayer K., Schuller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Dusterhoft A., Stiekema W., Entian K.D., Terryn N., Harris B., Ansorge W.,
RA Brandt P., Grivell L., Rieger M., Weichselgartner M., de Simone V.,
RA Obermaier B., Mache R., Muller M., Kreis M., Delseny M., Puigdomenech P.,
RA Watson M., Schmidtheini T., Reichert B., Portatelle D., Perez-Alonso M.,
RA Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H.,
RA Ridley P., Langham S.A., McCullagh B., Bilham L., Robben J.,
RA Van der Schueren J., Grymonprez B., Chuang Y.J., Vandenbussche F.,
RA Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E.,
RA Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E.,
RA Brandt A., Peters S., van Staveren M., Dirske W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Kotter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., Van Montagu M., Rogers J.,
RA Cronin A., Quail M., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M.,
RA Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M.,
RA Benes V., Rechmann S., Borkova D., Blocker H., Scharfe M., Grimm M.,
RA Lohnert T.H., Dose S., de Haan M., Maarse A., Schafer M., Muller-Auer S.,
RA Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A.,
RA Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O.,
RA Quigley F., Clabauld G., Mundlein A., Felber R., Schnabl S., Hiller R.,
RA Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C.,
RA Montfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sehkon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L., Nelson J.,
RA Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J.,
RA Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffmann J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002687; ANM66193.1; -; Genomic_DNA.
DR RefSeq; NP_001328102.1; NM_001340457.1.
DR AlphaFoldDB; A0A1P8B3M4; -.
DR SMR; A0A1P8B3M4; -.
DR STRING; 3702.A0A1P8B3M4; -.
DR ProteomicsDB; 199533; -.
DR EnsemblPlants; AT4G03490.3; AT4G03490.3; AT4G03490.
DR GeneID; 827426; -.
DR Gramene; AT4G03490.3; AT4G03490.3; AT4G03490.
DR Araport; AT4G03490; -.
DR TAIR; AT4G03490; -.
DR InParanoid; A0A1P8B3M4; -.
DR OrthoDB; 5476624at2759; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; A0A1P8B3M4; baseline and differential.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR026961; PGG_dom.
DR PANTHER; PTHR24186:SF18; ANKYRIN REPEAT FAMILY PROTEIN; 1.
DR PANTHER; PTHR24186; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF13962; PGG; 1.
DR SMART; SM00248; ANK; 9.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 446..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 524..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 552..577
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 35..62
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 347..368
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 439..547
FT /note="PGG"
FT /evidence="ECO:0000259|Pfam:PF13962"
SQ SEQUENCE 710 AA; 78412 MW; 9F00D2277F973620 CRC64;
MDPETYRAVV MGKVQEFEKV MEENEIPVLD QVTFQGNTIL HLAAIYGHDH LVRRILAYEL
NILRNWKRGL NCNFVPSFSH YQTLLVRRNY KGDLALHVAA AAGHKLIVGL LIDCLRQLPQ
DITMVIGSEQ MVIGNIFRVS NNDGNTALHL SLKGNHVSVS LQLVREDRST CFLLDKEDVS
PLYMAAEAGY VSLVEHMLRG LDASFVGKSV LCAAVKSQNL DILTAVLESD SDLVESRDED
GRTPLATAAS IGYDIGVQHM LTRFASSTQV AYIKNEDGSF PIHSACSARC TSALKVILKH
HPDTIEMLNS QGQNVLHVAA KSGNARAVGY LLRKSDVKRL INEQDIEGNT PLHLASSNSH
PKVVSLFIHD RRVDLKILNY KGFTALDAAE DHMATIPSLQ EWLIWMALVA AGTTRAPRVH
LRADIPGLTT DEDLILKIHK DRVNTLLVVA TLVATMAFAA GLSVPLGYNS TEFKSNVKHS
YEESAFHAFV ICNSIAVYTA VISTVALIGT QLADLKCMLT TFKFIVPLLG FSIIAMSLAF
VAGLYLVLGH HYWLAIFVLA SGGFYLMALL LLIIPYASPY TFTLSRSLNS LVQNMSKEDV
DSVNQLVPAP TEELALIKAI QVNRCIQGNI GVTSMMVPRK HTHNFRVPVL VARQQNNSGL
TALDIAELNP NPTTSFERNR LRVWLCVFSC FGISYRQLGA TVQFFICEKT
//
