ID A0A1P8BDT3_ARATH Unreviewed; 1807 AA.
AC A0A1P8BDT3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=E3 ubiquitin ligase {ECO:0000313|EMBL:ANM69765.1};
GN Name=EMB2771 {ECO:0000313|EMBL:ANM69765.1,
GN ECO:0000313|TAIR:AT5G05560};
GN Synonyms=anaphase promoting complex 1 {ECO:0000313|EMBL:ANM69765.1},
GN APC1 {ECO:0000313|EMBL:ANM69765.1}, EMBRYO DEFECTIVE 2771
GN {ECO:0000313|EMBL:ANM69765.1}, MOP10.10 {ECO:0000313|EMBL:ANM69765.1},
GN MOP10_10 {ECO:0000313|EMBL:ANM69765.1};
GN OrderedLocusNames=At5g05560 {ECO:0000313|Araport:AT5G05560,
GN ECO:0000313|EMBL:ANM69765.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:ANM69765.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:ANM69765.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130714; DOI=10.1038/35048507;
RG Kazusa DNA Research Institute;
RG Cold Spring Harbor and Washington University in St Louis Sequencing Consortium;
RG European Union Arabidopsis Genome Sequencing Consortium;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., See L.H., Vil D., Baker J.,
RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Dusterhoft A., Stiekema W., Pohl T., Entian K.D.,
RA Terryn N., Hartley N., Bent E., Johnson S., Langham S.A., McCullagh B.,
RA Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H.,
RA Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Lankhorst R.K., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S.,
RA Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J.,
RA Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K., Rudd S., Schoof H.,
RA Schueller C., Zaccaria P., Mewes H.W., Bevan M., Fransz P.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SIMILARITY: Belongs to the APC1 family.
CC {ECO:0000256|ARBA:ARBA00010547}.
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DR EMBL; CP002688; ANM69765.1; -; Genomic_DNA.
DR RefSeq; NP_001331419.1; NM_001342825.1.
DR SMR; A0A1P8BDT3; -.
DR ProteomicsDB; 199893; -.
DR EnsemblPlants; AT5G05560.2; AT5G05560.2; AT5G05560.
DR GeneID; 830439; -.
DR Gramene; AT5G05560.2; AT5G05560.2; AT5G05560.
DR Araport; AT5G05560; -.
DR TAIR; AT5G05560; EMB2771.
DR OrthoDB; 180933at2759; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; A0A1P8BDT3; baseline and differential.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR024990; Apc1.
DR InterPro; IPR048971; Apc1_3rd.
DR InterPro; IPR041221; APC1_C.
DR InterPro; IPR046794; Apc1_MidN.
DR InterPro; IPR049255; Apc1_N.
DR InterPro; IPR011989; ARM-like.
DR PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR Pfam; PF12859; ANAPC1; 2.
DR Pfam; PF21282; APC1_3rd; 1.
DR Pfam; PF18122; APC1_C; 1.
DR Pfam; PF20518; Apc1_MidN; 2.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A1P8BDT3,
KW ECO:0007829|ProteomicsDB:A0A1P8BDT3};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1349..1372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..266
FT /note="Anaphase-promoting complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12859"
FT DOMAIN 297..507
FT /note="Anaphase-promoting complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12859"
FT DOMAIN 521..693
FT /note="Anaphase-promoting complex subunit 1 middle"
FT /evidence="ECO:0000259|Pfam:PF20518"
FT DOMAIN 724..782
FT /note="Anaphase-promoting complex subunit 1 middle"
FT /evidence="ECO:0000259|Pfam:PF20518"
FT DOMAIN 1452..1525
FT /note="Anaphase-promoting complex subunit 1 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF21282"
FT DOMAIN 1593..1758
FT /note="Anaphase-promoting complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18122"
SQ SEQUENCE 1807 AA; 200435 MW; A72AD8AB31F3E2C0 CRC64;
MPPGVRQLTV LGKFKPFGLI AEATDGKSPD DSYQYFLFDP ELTGERDDAD GNDANFSRQR
EHELFIRDNC IIWTSGSRVL KRFTLSSAVI KACWSNLGRG TEAFLCVLQI ACLTIYNTSG
EVVSVPLMRT VKSIWPLPCG LLLEQAGEVN PPSHVPFSPV SPILGSREML RQRKEVGNSS
PQNFHSPVAH DLISKRDMPC MSSHLILRDP LEEPGPTYVE ERGKLTIMKD YDERTIWTSD
RLPLMTSYNK GKMQHSVWAA EFIESNLEAS ASCSSGIVPD AVLSKRVSFR RIWQAKGAKK
AASKVFLATD NSVPVICFLI LEQKKLLSVG LQTVEINNEI LFDVKPDISW SVSAIAAAPV
VVTRSQVKIG LLPHLDIIVL SPENDLFLYS GKQCLCRYVL PSWLGESIGS GDGESAKTDS
GFRNLKITGL SDAVLGSINL SVNHSQIFRC ALTGKPSSSL ANDCIAAIAE GLRSDLYSLF
LSLLWGDGHS DLQGSSIHFE WEALCNIFLE ICQKPTVVHR KQPKTASESS WEFLLISKFH
KTYSRFHNGI TSINRLDLEG IVPFDSKICS EETLGSSCEL MVQSLDCLHA VYESLKMDNL
RKQDLHHLAV LLCNIAKFLD EKCYLDYYIR DFPRLSTTIG ACTTLSSSRK PPNLFRWLEN
CLRRGCLSTN FDDLPDLIRR DGCSIVSWAR KVVSFYSVLF GDKPEGRTLS SGVPCNIAPG
SYSCNEELTI LAMAGERFGL HQLDLLPSGV SLPLRHALDS CRESPPADWP AIAYVLLGRE
DMALSVFRNF SSSKEFEMQS NTSLISMSIP YMLHLHPVIV PSSESIGLEN TKIEDTNSVD
GSVIDGMEHI FNSYTQLRYG RDLRLNEVRR LLCSARPVVV QTAANPTISD QEQQQDHLWR
IAQRTAVLPL GRGAFTLSTI HTLLTEAFTV PKLVLAGRLP SQQNAIVNLD PNIRNIQELK
TWPEFHNAVA AGLRLAPLQG KVSRTWIRYN KPGEPNAVHA GLLFGLGLQG YLHVLNLSDI
YQYFTQDHES TTVGLMLGLA ASYRGTMQPD IAKALFFHVP ARYQASYTEF EIPTLLQSAA
LVSVGMLFEG SAHQQTMQLL LGEIGRRSAG DNVLEREGYA VSAGFSLGLV ALGRGGDALG
SMDSLVNRLL LYLGAKEERS ILVPSLEDHR SAAQITDGST SNVDITAPGA IIALTLMYLK
TESEVIFSKL SIPQTHYDLE CVRPDFIMLR VIARNLIMWS RICPTCDWIQ SQVPEVVKNG
ISQLRDDMDN MYEVDVEALV QAYVNIVAGA CISLGLRFAG TRDGNARDLL NSYALYLLNE
IKPLSATPGN AFPRGISKFV DRGTLEMCLY LIIISLSVVM AGSGDLQVFR LLRFLRSRNS
ADGHANYGTQ MAVSLATGFL FLGGGMRTFS TNNGSLAMLL ITLYPRLPSG PNDNRCHLQA
FRHLYVLATE ARWLQTIDVD SGLPVYAPLE VTVKETKLYS ETKFCEITPC ILPERAILKR
ICVCGPRYWP QQIELVPEEK NWWSFGDKSD PFSSGVIYVK RKVGACSYVD DPVGCQSLLS
RAMHKVFGLR TLGESNLIAN SHRELDSDSV DHLVSTFSSD PSLIAFAQLC CDKSWNNRSD
SEFKEFCLQV LFDCISKDRP ALLQVYLSLY TTIGSMADLL VKSDSNMCDS LSISSLKVAL
AYNEAVSTGR LASSGGFVQS IFLASLRKRC EEVLNCSTEL KINLRNYLTS EAWPYDKNSK
LQKDIIILSW YLKWFNVPSP SIIKAAVEKI KSKSKNSTSA IPLLRLLLPN THISVIGEID
RVFFPSN
//
