ID   A0A1P8F4X3_9CHLR        Unreviewed;       345 AA.
AC   A0A1P8F4X3;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=L-threonine aldolase {ECO:0000313|EMBL:APV43478.1};
DE            EC=4.1.2.5 {ECO:0000313|EMBL:APV43478.1};
GN   Name=ltaE {ECO:0000313|EMBL:APV43478.1};
GN   ORFNames=Dform_00115 {ECO:0000313|EMBL:APV43478.1};
OS   Dehalogenimonas formicexedens.
OC   Bacteria; Chloroflexota; Dehalococcoidia; Dehalogenimonas.
OX   NCBI_TaxID=1839801 {ECO:0000313|EMBL:APV43478.1, ECO:0000313|Proteomes:UP000185934};
RN   [1] {ECO:0000313|Proteomes:UP000185934}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NSZ-14 {ECO:0000313|Proteomes:UP000185934};
RA   Key T.A., Bowman K.S., Lee I., Chun J., Albuquerque L., da Costa M.S.,
RA   Rainey F.A., Moe W.M.;
RT   "Dehalogenimonas formicexedens sp. nov., a chlorinated alkane respiring
RT   bacterium isolated from contaminated groundwater.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the threonine aldolase family.
CC       {ECO:0000256|ARBA:ARBA00006966}.
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DR   EMBL; CP018258; APV43478.1; -; Genomic_DNA.
DR   RefSeq; WP_076003291.1; NZ_CP018258.1.
DR   AlphaFoldDB; A0A1P8F4X3; -.
DR   STRING; 1839801.Dform_00115; -.
DR   KEGG; dfo:Dform_00115; -.
DR   OrthoDB; 9774495at2; -.
DR   Proteomes; UP000185934; Chromosome.
DR   GO; GO:0004793; F:threonine aldolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   CDD; cd06502; TA_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR023603; Low_specificity_L-TA-like.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   NCBIfam; NF041359; GntG_guanitoxin; 1.
DR   PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR   PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   PIRSF; PIRSF017617; Thr_aldolase; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:APV43478.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000185934}.
FT   DOMAIN          5..289
FT                   /note="Aromatic amino acid beta-eliminating lyase/threonine
FT                   aldolase"
FT                   /evidence="ECO:0000259|Pfam:PF01212"
FT   MOD_RES         203
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR017617-1"
SQ   SEQUENCE   345 AA;  36887 MW;  AFE1E6AD6AE0C158 CRC64;
     MKFIDFRSDT ITHPTQEMRD AMYRAEVGDD VFGEDPTVNR LEAIAAEITG KEAAVFTPSG
     TMSNLIAVLS HTRHGDEIIL GDRAHIFLNE AGGAAAIGGV SLRTVPNNTD GTIDIDRIDS
     SVRGTGNLHW PTSRLLCLEN THNYCGGAVL DVEYTAEASE AAHRRGLTVH LDGARLFNAA
     VALGVAPVEL CEPVDSVNFC LSKGLSAPIG SVLCGNTEFI ARARKFRKMV GGGMRQAGVI
     AAAGIVCLEH CVDRLADDHK NARTLADGLR QIPGLVVENP QTNIVMIDLP DNLLAADFVK
     RAAEAGIKFI SVGSRRVRAV THRMVSAADI AEAITRLKKA MGQLK
//