ID A0A1P8F9H6_9CHLR Unreviewed; 344 AA.
AC A0A1P8F9H6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Precorrin-8X/cobalt-precorrin-8 methylmutase {ECO:0000313|EMBL:APV45114.1};
DE EC=5.4.99.60 {ECO:0000313|EMBL:APV45114.1};
DE EC=5.4.99.61 {ECO:0000313|EMBL:APV45114.1};
GN ORFNames=Dform_01795 {ECO:0000313|EMBL:APV45114.1};
OS Dehalogenimonas formicexedens.
OC Bacteria; Chloroflexota; Dehalococcoidia; Dehalogenimonas.
OX NCBI_TaxID=1839801 {ECO:0000313|EMBL:APV45114.1, ECO:0000313|Proteomes:UP000185934};
RN [1] {ECO:0000313|Proteomes:UP000185934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NSZ-14 {ECO:0000313|Proteomes:UP000185934};
RA Key T.A., Bowman K.S., Lee I., Chun J., Albuquerque L., da Costa M.S.,
RA Rainey F.A., Moe W.M.;
RT "Dehalogenimonas formicexedens sp. nov., a chlorinated alkane respiring
RT bacterium isolated from contaminated groundwater.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
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DR EMBL; CP018258; APV45114.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1P8F9H6; -.
DR STRING; 1839801.Dform_01795; -.
DR KEGG; dfo:Dform_01795; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000185934; Chromosome.
DR GO; GO:0043778; F:cobalt-precorrin-8 methylmutase activity; IEA:UniProtKB-EC.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:UniProtKB-EC.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03416; CbiX_SirB_N; 1.
DR Gene3D; 3.40.50.1400; -; 1.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR002762; CbiX-like.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR Pfam; PF01903; CbiX; 1.
DR SUPFAM; SSF53800; Chelatase; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:APV45114.1};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000185934}.
FT DOMAIN 146..340
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 344 AA; 36849 MW; 533F4EE92D39EA45 CRC64;
MTIKTSQPAV IILSHGSPKA DSVIPIMTGL CARLKRYLAP GVEIRWAAMQ FNHPTLAESA
ATLYDEGFRN VVVMPYFLYS GQHVSHDIPG MMDEISKQYS DLKLKLAGTL DRAESLIELV
AERLGTASPE LLPHFEDSAV ASRPEDIEAL SMEIIEANLP ELPFNRSEKE VVKRLIHASG
EIPLASKIQM TSGAVDSGIA ALRAGKGVFT DVRMVGAGVN RANAEKLGVQ VFCALDEKDL
ADEAKATNQT RSAVAIKRLA DRIDGAIVAI GNAPTALYAL LDLIDAGQVR PALVIGMPVG
FVQAKESKEA LVKRDVPYIT VRGTRGGSNL AAAAVNALMK LAIR
//
