ID A0A1P8FIE8_9PROT Unreviewed; 329 AA.
AC A0A1P8FIE8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:APV49820.1};
GN ORFNames=BWI17_09095 {ECO:0000313|EMBL:APV49820.1};
OS Betaproteobacteria bacterium GR16-43.
OC Bacteria; Pseudomonadota; Betaproteobacteria.
OX NCBI_TaxID=1904640 {ECO:0000313|EMBL:APV49820.1, ECO:0000313|Proteomes:UP000185830};
RN [1] {ECO:0000313|EMBL:APV49820.1, ECO:0000313|Proteomes:UP000185830}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GR16-43 {ECO:0000313|EMBL:APV49820.1,
RC ECO:0000313|Proteomes:UP000185830};
RA Choi A.;
RT "Complete genome sequence of betaproteobacterium GR16-43, isolated from a
RT freshwater pond in South Korea.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP019169; APV49820.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1P8FIE8; -.
DR STRING; 1904640.BWI17_09095; -.
DR KEGG; beba:BWI17_09095; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000185830; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 234..328
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 329 AA; 37047 MW; 3F20EE116CB69D41 CRC64;
MQPAAEKGLI PVTILTGFLG AGKTTLLNRI LTEQHGERIA VIENEFGESG IDNEILVQDK
EEQIVEMNNG CLCCTVRGDL VRILKDLRRK KRGGEVKFDR VIIETTGLAN PGPVAQTFFM
DEDVHKDYLL DAIVTVVDAK HGQQTLDEHD EARAQVGFAD RILLSKTDLV AESETTALMD
RLRSMNPRAH QKKVHFGEAD IKEILDIRGF NLNAVLEVSP EFLTDDHHHH DDDVKSFVWK
DARPLDMDKI ETFLSLMVQN YGENLLRYKG VLNVKDEPRR MIFQGVHMLM GGTPGKPWEA
GEARESVMVF IGKGIPRRLF EEGLTYCVA
//
