ID A0A1P8K5X2_9BURK Unreviewed; 308 AA.
AC A0A1P8K5X2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Oxidoreductase {ECO:0000313|EMBL:APW41424.1};
GN ORFNames=RS694_01890 {ECO:0000313|EMBL:APW41424.1};
OS Rhodoferax saidenbachensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Rhodoferax.
OX NCBI_TaxID=1484693 {ECO:0000313|EMBL:APW41424.1, ECO:0000313|Proteomes:UP000186110};
RN [1] {ECO:0000313|EMBL:APW41424.1, ECO:0000313|Proteomes:UP000186110}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22694 {ECO:0000313|EMBL:APW41424.1,
RC ECO:0000313|Proteomes:UP000186110};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HIBADH-related family.
CC {ECO:0000256|ARBA:ARBA00009080}.
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DR EMBL; CP019239; APW41424.1; -; Genomic_DNA.
DR RefSeq; WP_029709724.1; NZ_CP019239.1.
DR AlphaFoldDB; A0A1P8K5X2; -.
DR STRING; 1484693.RS694_01890; -.
DR KEGG; rsb:RS694_01890; -.
DR eggNOG; COG2084; Bacteria.
DR Proteomes; UP000186110; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF15; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000186110}.
FT DOMAIN 17..181
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 187..306
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 193
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 308 AA; 32340 MW; 190E31F6FD3585E0 CRC64;
MPNINDKTYE PSPAYSVAFL GLGVMGYPMA GHLARAGHQV TVYNRTATKS IAWCAEFAGA
TSQNGAHNHG STPRLAVQNA DIVFCCVGND ADLRSVVLGA DGAFAGMKPG AIFVDHTTAS
ANVARELSAT ARTKGLQFVD APVSGGQAGA QNGLLTVMCG GDAAAFETVK PVAMAFSRAF
TLLGDSGAGQ LAKMVNQICI AGLVQGLSEA VAFGQKAGLD MNQVLDVIGK GAAQSWQMDN
RGKTMVADKF DFGFAVDWMR KDLGLVLDEA KRNGARLPVT ALVDQFYADV QQMGGQRWDT
SSLIKRLK
//
