ID A0A1P8L627_9CAUD Unreviewed; 840 AA.
AC A0A1P8L627;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=DNA polymerase {ECO:0000313|EMBL:APW79713.1};
GN ORFNames=PP99_22 {ECO:0000313|EMBL:APW79713.1};
OS Pectobacterium phage PP99.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Autographiviridae; Gajwadongvirus; Gajwadongvirus PP99.
OX NCBI_TaxID=1932883 {ECO:0000313|EMBL:APW79713.1, ECO:0000313|Proteomes:UP000221883};
RN [1] {ECO:0000313|Proteomes:UP000221883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR EMBL; KY250034; APW79713.1; -; Genomic_DNA.
DR Proteomes; UP000221883; Genome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR GO; GO:0039693; P:viral DNA genome replication; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.370; -; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR019760; DNA-dir_DNA_pol_A_CS.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF62; DNA POLYMERASE THETA; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS00447; DNA_POLYMERASE_A; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00023109};
KW Reference proteome {ECO:0000313|Proteomes:UP000221883};
KW Viral DNA replication {ECO:0000256|ARBA:ARBA00023109}.
FT DOMAIN 545..741
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|SMART:SM00482"
SQ SEQUENCE 840 AA; 95881 MW; B01BDCC6DB22564E CRC64;
MFADKKERPS GKGRFLVGDL ESVGLIRATR KASDIHILTL QDYFSGEYWI FFDPYEKRIN
PSKLEMEGDQ DGYIEDGVRM LMESEAFSFQ NGVGFDLHVF ERCFPWFKYN YLESRASRPH
ADIFPFKYMD TMLVSQLTYP DRPLPPQAYA IGAGNTGPHS IAAHGIRMGR YKPDHEDWST
LTDAMIHRNV EDVAIGTDML KWLMEGDWAE QKARGLNKTT GCGIETAYQM EQQVALMISR
QEQRGFRFDM AQAYKDFCTI DKEMEDTAAA VDPLIPLRLV TKPYKFADLK SRYDAAVKAG
FAEAELKPIF NCINQTMKAM GDEGRMGDKA TMWSLTTKNG DYSKRLQGYF PEMRGNINDT
HDPLVAGAFT PISFEHIGLG NLDYIKEKVL YPLGWSGVNL SDSEQEWYDE HGTTRYPWAG
KIDDDSLELW KKKQEVPEWA QQVVNYYILR SRRSVILNRG DLDHFLEKGQ WPKQKNGRHE
CRGLLAVAYS KEYDIMAMEY FAKFREWPTD PDEDWRVPAA AFSIGTNTFR MRHRFVVNIP
ARGLWPLRNL FIASKGKMIL GCDGAGLELR MLSHFMNDPE YQDIILTGDI HTHNQLKAGL
PTRDMAKTFI YAFLYGSGID GLARLAGISF SEMEQCIARF KAELPALAKL IERVETAGRK
FGYLQAIDGR WGRIRRKNGK PLLHTALNVL LQMTGSLVMK YGECIAESQM IEEGVALDDL
GFPAFVANVH DEVQMEVPED EVLTMEYSLP YTLDGFENEK KAIKAVFDVE EKRSHTDEQG
RKWSAAAKVS AADGVIVCRR MYHRAGHILM DAFEASGVKF NMRCPLAGEY KIGYSWHDTH
//
