ID A0A1P8R3A9_9GAMM Unreviewed; 401 AA.
AC A0A1P8R3A9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Beta-ketoadipyl CoA thiolase {ECO:0000313|EMBL:APX93200.1};
GN ORFNames=BWR19_09795 {ECO:0000313|EMBL:APX93200.1};
OS Halomonas sp. 1513.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1883416 {ECO:0000313|EMBL:APX93200.1, ECO:0000313|Proteomes:UP000187327};
RN [1] {ECO:0000313|Proteomes:UP000187327}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1513 {ECO:0000313|Proteomes:UP000187327};
RA Shuang W.;
RT "Complete genome sequence of Haloterrigena daqingensis type strain
RT (JX313T).";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP019326; APX93200.1; -; Genomic_DNA.
DR RefSeq; WP_076748068.1; NZ_CP019326.1.
DR AlphaFoldDB; A0A1P8R3A9; -.
DR STRING; 1883416.BWR19_09795; -.
DR KEGG; halo:BWR19_09795; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000187327; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR PANTHER; PTHR43853:SF2; 3-OXOADIPYL-COA_3-OXO-5,6-DEHYDROSUBERYL-COA THIOLASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000187327};
KW Transferase {ECO:0000256|RuleBase:RU003557}.
FT DOMAIN 5..266
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 276..399
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 89
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 356
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 386
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 401 AA; 41477 MW; 074008B20C484D19 CRC64;
MQDAYIYDGL RTPFGRHGGG LANVRPDDLL GQVLKSLVAR NGFGLEAYEE VLAGCTNQAG
EDSRNVARHA GLVAGLPVEV AAQTVNRLCG SGLAAVIDAA RATRLGEGEL FLAGGVESMS
RAPYVLGKAQ TAFARNQPMY DTVIGARFPN PWIAQQFGSH SMPETADNVA HDLAISREAG
DAFAARSQAR YATALERGFY DDELLAVEVP QGRKQPPLTV DMDEHPRPGT DAGKLGKLGA
LFDGGVVTAG NASGLNDGAA ALIVGSRAAG ERAGVAPRAR IVASALAGVP PRVMGLGPVP
ASRKALERAG LSLAQMDVIE INEAFAVQVL GCAKQLELDP DDSRLNANGG AIAIGHPLGA
SGARLALTAL RQLEASGGRY ALVTMCIGVG QGIACVLERL D
//
