ID A0A1P8R686_9GAMM Unreviewed; 726 AA.
AC A0A1P8R686;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BWR19_14645 {ECO:0000313|EMBL:APX94072.1};
OS Halomonas sp. 1513.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1883416 {ECO:0000313|EMBL:APX94072.1, ECO:0000313|Proteomes:UP000187327};
RN [1] {ECO:0000313|Proteomes:UP000187327}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1513 {ECO:0000313|Proteomes:UP000187327};
RA Shuang W.;
RT "Complete genome sequence of Haloterrigena daqingensis type strain
RT (JX313T).";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP019326; APX94072.1; -; Genomic_DNA.
DR RefSeq; WP_076748936.1; NZ_CP019326.1.
DR AlphaFoldDB; A0A1P8R686; -.
DR STRING; 1883416.BWR19_14645; -.
DR KEGG; halo:BWR19_14645; -.
DR OrthoDB; 9797243at2; -.
DR Proteomes; UP000187327; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.20.120.160; HPT domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR036641; HPT_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF01627; Hpt; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47226; Histidine-containing phosphotransfer domain, HPT domain; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50894; HPT; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000187327};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 235..452
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 476..593
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 628..723
FT /note="HPt"
FT /evidence="ECO:0000259|PROSITE:PS50894"
FT MOD_RES 525
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 667
FT /note="Phosphohistidine"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00110"
SQ SEQUENCE 726 AA; 78355 MW; 9D12ACEF6DE76A04 CRC64;
MLRYPGRLKL GAIAALLFFI AAITVAGLVL WRQDSLAQSV GGDAAWSAYK LDREAIQLRS
QLARPADQGT LSDLRLRFEL MYSRVNLLRR GELAELLDSI PRASSLMASI GDQVDAIDER
LYREDFSLEQ DGRDALDARL DTLSRYSEEL IVAINAHLAD TTTHEREQLQ GLYRLLLGLI
MAMSAAAALV VVFLFREARE SAAARRATEA LSGELEITAR RAEAASQAKS EFLATVSHEI
RTPLNGVIGM SELLRERPLD ATSRHYAATI HESGGLLLGL INDILDFSKI EAGRLELEHT
DYDLRELMAQ AVALFAPRAS AKSLTLRSEC DPRLPARLSG DPGRVNQIIL NLLSNAIKFS
TRGEVVLAAQ RGEDEGLEIS VSDQGCGIDE GQRDLLFEPF RQGDPSTARR FGGSGLGLAI
CKQLASAMDG EIDFTSAPGQ GSRFWLRLPL QPAMAADTVV PASRPHVATA VNFGASLLLV
EDNPINQQVA VAMLERLGCR VTVAASGSEA LACCEAQRFA LIFMDVQMPD LDGLAVTRAL
RQRDGWTRQV PIVAMTAGAL DGDQARCREA GMDGYLAKPL FRETLLAMLE RHLPDAPHPA
PAASPDTPDE ASTWLDGAAL EELEASLALA DRQALLALFQ SNMPARLDQL EAARAADDLA
RTAQLAHLIK GEAGSLGLGR LAAAAQRLEQ AAAQQAPCQA ALEALRDCLA PSLAALARRW
PASETS
//
