ID A0A1P8UZL4_9RHOB Unreviewed; 748 AA.
AC A0A1P8UZL4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
DE Flags: Precursor;
GN ORFNames=Ga0080574_TMP4505 {ECO:0000313|EMBL:APZ54839.1};
OS Salipiger abyssi.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Salipiger.
OX NCBI_TaxID=1250539 {ECO:0000313|EMBL:APZ54839.1, ECO:0000313|Proteomes:UP000187059};
RN [1] {ECO:0000313|EMBL:APZ54839.1, ECO:0000313|Proteomes:UP000187059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JLT2014 {ECO:0000313|EMBL:APZ54839.1,
RC ECO:0000313|Proteomes:UP000187059};
RA Tang K.;
RT "Deep-sea bacteria in the southern Pacific.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP015093; APZ54839.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1P8UZL4; -.
DR STRING; 1250539.Ga0080574_TMP4505; -.
DR KEGG; paby:Ga0080574_TMP4505; -.
DR OrthoDB; 9796100at2; -.
DR Proteomes; UP000187059; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000187059};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:APZ54839.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..748
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011958719"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 384..607
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 631..747
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 682
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 748 AA; 80701 MW; 7249E071CDB29EB7 CRC64;
MVLLALACFG SVMALPAGAA QIGLLAAGAG FATLAALVAL GHLLRRRRGA RDFAAIVRFS
QDVPTPIFVT DESETVIFAN AAACDRFGAP EARPLAAVLN ASIASAEGVM HRLRLAAGDN
DSGAAREDVT THAGRFRLSL HLGFGGRAIW RVDPRAGPDR DAGAGAADEA ELPLLTLGRS
GAVLYMNGRA RAVLGRRVKR IEDVLEDPPL SSGAVHRFVT PDGHRSFTVR CADAGIGRQE
LILHPVETAQ GDTPDMTGFD ALPVPLLRLG ADGTVLRANA VACRLLAVEH ADGGCVTDYM
EGLGRSITDW LSEAAAGRGL HRSEFLRLTR ADREIYVQVT LNQVHNNGRP ELVAVLNDAT
ELKTLEAQFV QSQKMQAIGQ LAGGVAHDFN NLLTAISGHC DLLLLRHDQG DPDYGDLVQI
NQNANRAAAL VGQLLAFSRK QTLRPEVLDL RDTLSDLTHL LNRLVGEKVQ LTLSHDPVLP
TIRGDRRQLE QVMMNLVVNA RDAMPEGGEI TIETERRTLL DPLKRDRALV EPGEYAAVKV
IDRGAGIPQD KLQKVFEPFY TTKRTGEGTG LGLSTVYGIV KQTGGFIFVD SVIGQGSCFT
LLFPAYDAPA QLPPPQHREK PRKRAQQGNG VVLLVEDEAP VRAFAARALR LRGYTVIEAG
TAEDALDTLA DDMVRVDIFV TDVVMPGMDG PTWVRKALEA RPGTRVVFVS GYAEDVFAEG
EDEVPNSVFL PKPFSLNQLT ETVQRQLH
//
