ID A0A1P8WCX9_9PLAN Unreviewed; 1184 AA.
AC A0A1P8WCX9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Potassium efflux system KefA {ECO:0000313|EMBL:APZ91901.1};
DE Flags: Precursor;
GN Name=kefA {ECO:0000313|EMBL:APZ91901.1};
GN ORFNames=Fuma_01497 {ECO:0000313|EMBL:APZ91901.1};
OS Fuerstiella marisgermanici.
OC Bacteria; Planctomycetota; Planctomycetia; Planctomycetales;
OC Planctomycetaceae; Fuerstiella.
OX NCBI_TaxID=1891926 {ECO:0000313|EMBL:APZ91901.1, ECO:0000313|Proteomes:UP000187735};
RN [1] {ECO:0000313|EMBL:APZ91901.1, ECO:0000313|Proteomes:UP000187735}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NH11 {ECO:0000313|EMBL:APZ91901.1,
RC ECO:0000313|Proteomes:UP000187735};
RX PubMed=28066393; DOI=10.3389/fmicb.2016.02079;
RA Kohn T., Heuer A., Jogler M., Vollmers J., Boedeker C., Bunk B., Rast P.,
RA Borchert D., Glockner I., Freese H.M., Klenk H.P., Overmann J.,
RA Kaster A.K., Rohde M., Wiegand S., Jogler C.;
RT "Fuerstia marisgermanicae gen. nov., sp. nov., an Unusual Member of the
RT Phylum Planctomycetes from the German Wadden Sea.";
RL Front. Microbiol. 7:2079-2079(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; CP017641; APZ91901.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1P8WCX9; -.
DR STRING; 1891926.Fuma_01497; -.
DR KEGG; fmr:Fuma_01497; -.
DR OrthoDB; 9809206at2; -.
DR Proteomes; UP000187735; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR InterPro; IPR025692; MscS_IM_dom1.
DR InterPro; IPR024393; MscS_porin.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR Pfam; PF12795; MscS_porin; 1.
DR Pfam; PF12794; MscS_TM; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000187735};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..1184
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010184420"
FT TRANSMEM 540..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 586..609
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 615..638
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 666..686
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 698..715
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 740..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 774..793
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 851..873
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 912..933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 954..975
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 981..1008
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 71..293
FT /note="Mechanosensitive ion channel MscS porin"
FT /evidence="ECO:0000259|Pfam:PF12795"
FT DOMAIN 543..879
FT /note="Mechanosensitive ion channel inner membrane"
FT /evidence="ECO:0000259|Pfam:PF12794"
FT DOMAIN 996..1061
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 1070..1152
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
FT REGION 1163..1184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 255..282
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 409..436
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1184 AA; 131842 MW; 8287934652C6A908 CRC64;
MFQNLAHRRQ RWVAVLWPCA LLVLISLACP VLNAQTTAQP PNATAEKQEE EVAAPRTETV
TAEQLDQLKK QIEGATDLDE EAKKKVLDTW QKAADALARA VKMEAQAPLD LAAIEKTAAT
AKDIQTKLAA APDPALADLP SDPSLADLTS ALAARQPRLQ DAKQKLISLE AEPARRIERR
AAIVGDQSTL AGRKEAIEKE LAAPAPADES AFATAARRAL LQARLREVIA EGPAHAAELA
KYDASKAVDL PTLRIQEARK EVTRLQQEID TLNKRITARR SNDARYIAEQ LELFAQGEPV
PTPYDVNGTG GQLYSEALTE PNALATATTT AELADENVDV TSNLAQATND LTTANRTLEA
FRARRIKTKE GIDRVGLTGA IGLELRRQLR SLADPGVIRQ RCRDRQEKMR DVEFRRLDLE
DQAEQVEQQM ELLKLRDSRS AEDEKELRLA TDRYTTLVTL EKSLGEYFNR LGELDATEQE
YFREIEEFST FIRERVLWIR SNRLPGHDDA GELIGTIKWF VSPVNWNRVR ETIWKDAKEY
VGLYGLITLL ITLLFVIQGR FRHSLTRIAE VTARSTCREF MPTIRAAVLT AILALAWPAL
PAFFCWRLLS DAAASPLVLA VGEGLLAVTV GSLTLNLLRQ LCRPSGLGLA HFEWSANAVR
LLRSRIYSLM LLLLPLLFVE TTLNAHENPQ GRDSLERLVF VVSLIVLALF QYRVLHPKTG
VFRDYLAANT SSFPFRLRWL LFWAAVMLPL TLAALAIIGY YYTAYELSWR LHVTTWVLIS
LLVLRAFLIR WFVVSHRRLR IEQARQRRQS LAEEAKAEAS QSGLPKPAPQ EAAVDLQEVS
QQTQRFIDSG LAILGLVVIW FVWVNVLPAL GILDRWGLWE TSADVTVEYT DQEGRKGFRT
EPKIEWVTVA DVLIAIVLTV LTFTAASNIP GLLEITILQR LPLEPASRYA CRMVGRYLIV
VVGLVLATNA IGIGWSQVQW LAAALTVGLG FGLQEIFANF VSGLIILFER PVRIGDIVTI
GEVSGSVSRI QIRATTITDW DRKEYIVPNK EFVTGRLLNW TLSDTTNRVL INVGVAYGSN
TEKARQLLLE TASSHPNVLT DPAPVATFEG FGDSTLNLFL RCYLPNLDNR LATITDLHES
IDRAFKVAGI EIAFPQQDLH IRSVPPTLGN NSGPSSSDSY GESP
//
