ID A0A1P8WZW0_9SPHN Unreviewed; 348 AA.
AC A0A1P8WZW0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=BWQ93_14750 {ECO:0000313|EMBL:APZ99605.1};
OS Sphingopyxis sp. QXT-31.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=1357916 {ECO:0000313|EMBL:APZ99605.1, ECO:0000313|Proteomes:UP000188055};
RN [1] {ECO:0000313|EMBL:APZ99605.1, ECO:0000313|Proteomes:UP000188055}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QXT-31 {ECO:0000313|EMBL:APZ99605.1,
RC ECO:0000313|Proteomes:UP000188055};
RA Liang J.S.;
RT "Microbe-microbe interactions indirectly alter the fate of arsenic in
RT presence of MnII.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR EMBL; CP019449; APZ99605.1; -; Genomic_DNA.
DR RefSeq; WP_077031214.1; NZ_CP019449.1.
DR AlphaFoldDB; A0A1P8WZW0; -.
DR STRING; 1357916.BWQ93_14750; -.
DR KEGG; sphq:BWQ93_14750; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000188055; Chromosome.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000188055}.
FT DOMAIN 13..336
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 348 AA; 37468 MW; 4558A6783C1B54DD CRC64;
MTEDVLVAQQ GAIGRLSLNR PKAIHALNLD MVHAMTDALV AWKDDPAVQA VLLDHSEGRG
FCAGGDIAFL RNSALTDDGV SGRRFFHDEY QLNHLLFTYA KPVVAFMDGI TMGGGVGIAL
PAKYRVATEN TRLAMPETGI GLFPDVGGGW YLSRLEGRVG PFLALTGARL DGAECLALGL
ATHYLPVDKL AEAKARIAEH PDRIGGILGE LSATPPEAKI LTHIADINRL FASDKLEDIL
AALEADPGEW AAKELAALRT KSPQTCKVAL RQLADSLSLP DFAANMAMEY RIGSRVLTRP
DFAEGVRAVI VEKDNKPQWN PATAEGVSDE LIAAIFEPLP AQEEWTPL
//
