ID A0A1P8XSX6_9ACTN Unreviewed; 486 AA.
AC A0A1P8XSX6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Glutamate synthase {ECO:0000313|EMBL:AQA11304.1};
GN Name=gltD {ECO:0000313|EMBL:AQA11304.1};
GN ORFNames=BV401_13265 {ECO:0000313|EMBL:AQA11304.1};
OS Streptomyces autolyticus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=75293 {ECO:0000313|EMBL:AQA11304.1, ECO:0000313|Proteomes:UP000187851};
RN [1] {ECO:0000313|Proteomes:UP000187851}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC0516 {ECO:0000313|Proteomes:UP000187851};
RA Yin M., Jiang M., Lu T.;
RT "Streptomyces autolyticus CGMCC0516 complete genome sequence.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
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DR EMBL; CP019458; AQA11304.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1P8XSX6; -.
DR STRING; 75293.BV401_13265; -.
DR KEGG; sauo:BV401_13265; -.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000187851; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016639; F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006537; P:glutamate biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR006005; Glut_synth_ssu1.
DR InterPro; IPR009051; Helical_ferredxn.
DR NCBIfam; TIGR01317; GOGAT_sm_gam; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Glutamate biosynthesis {ECO:0000256|ARBA:ARBA00023164};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 40..130
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 146..456
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 486 AA; 52892 MW; 02E053086CCE32B9 CRC64;
MADPKGFLTT GREVAETRPV ETRVKDWNEV YVPGSLLPII SKQAGRCMDC GIPFCHNGCP
LGNLIPEWND YAYREDWREA SERLHATNNF PEFTGRLCPA PCESACVLGI NQPPVTIKNV
EVTIIDKAWD AGDVTPQPPE RLSGKTVAVI GSGPAGLAAA QQLTRAGHTV AVYERADRIG
GLLRYGIPEF KMEKRHINRR IEQMRAEGTK FRTETEIGRD IDAAKLRKRY DAVVIAAGAT
TSRDLPVPGR ELNGIHFAME YLPLANKVQE GDLTTAPITA EGKHVVVIGG GDTGADCVGT
AHRQGAASVT QLEIMPRPGD ERNANQPWPT FPMLYKVTSA HEEGGERLYS VSTSHFEGDE
DGNVQWLHLI EVEFKDGKLE QKPGTERRIP AQLVTLAMGF TGTDQKNGLV EQFGLELDQR
GNIARDADFA TNVPGVFVAG DAGRGQSLIV WAIAEGRSAA RGVDRYLAGA SELPAPIRPT
DRALVV
//
