ID   A0A1P8XTU8_9ACTN        Unreviewed;       339 AA.
AC   A0A1P8XTU8;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=NADP-dependent oxidoreductase {ECO:0000313|EMBL:AQA11657.1};
GN   ORFNames=BV401_15405 {ECO:0000313|EMBL:AQA11657.1};
OS   Streptomyces autolyticus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=75293 {ECO:0000313|EMBL:AQA11657.1, ECO:0000313|Proteomes:UP000187851};
RN   [1] {ECO:0000313|Proteomes:UP000187851}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC0516 {ECO:0000313|Proteomes:UP000187851};
RA   Yin M., Jiang M., Lu T.;
RT   "Streptomyces autolyticus CGMCC0516 complete genome sequence.";
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP019458; AQA11657.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1P8XTU8; -.
DR   STRING; 75293.BV401_15405; -.
DR   KEGG; sauo:BV401_15405; -.
DR   OrthoDB; 9805663at2; -.
DR   Proteomes; UP000187851; Chromosome.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd05288; PGDH; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR041694; ADH_N_2.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR045010; MDR_fam.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR   PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR   Pfam; PF16884; ADH_N_2; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          22..335
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   339 AA;  36460 MW;  AC76D6C17774286E CRC64;
     MSVIPTTGRE WHLVARPQGW PKPEDFALRE APVSEPAPGR ALVRNLYMSV DPYMRGRMND
     VKSYSPPFQL DEPMQGGAVG KVIASNAEGL SVGDHVLHFG GWREYAVVDD KSAVKVDPEI
     APLPAYLGVL GMPGLTAYAG LLEVASFKEG DAVFVSGAAG AVGSEVGQIA KLKGASRVIG
     SAGSDEKVQL LLDEYGFDAA FNYKNGPVGE QLKEAAPDGI DVYFDNVGGE HLEAAISRLK
     VHGRITACGM IAQYNATEPP AAPRNLAMVI GKRLRIQGML VGDHQHLQDQ FFQEVGGWIR
     EGKLHYRETV VKGVENAVDA FLGMLRGENT GKMIVAFED
//