ID A0A1P8XUI8_9ACTN Unreviewed; 872 AA.
AC A0A1P8XUI8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=BV401_16890 {ECO:0000313|EMBL:AQA11897.1};
OS Streptomyces autolyticus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=75293 {ECO:0000313|EMBL:AQA11897.1, ECO:0000313|Proteomes:UP000187851};
RN [1] {ECO:0000313|Proteomes:UP000187851}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC0516 {ECO:0000313|Proteomes:UP000187851};
RA Yin M., Jiang M., Lu T.;
RT "Streptomyces autolyticus CGMCC0516 complete genome sequence.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP019458; AQA11897.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1P8XUI8; -.
DR STRING; 75293.BV401_16890; -.
DR KEGG; sauo:BV401_16890; -.
DR OrthoDB; 137117at2; -.
DR Proteomes; UP000187851; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR031634; PknG_rubred.
DR InterPro; IPR031636; PknG_TPR.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR24363; SERINE/THREONINE PROTEIN KINASE; 1.
DR PANTHER; PTHR24363:SF0; SERINE_THREONINE-PROTEIN KINASE DDB_G0277989-RELATED; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF16919; PknG_rubred; 1.
DR Pfam; PF16918; PknG_TPR; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AQA11897.1};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527,
KW ECO:0000313|EMBL:AQA11897.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 236..519
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 41..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 526..554
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 872 AA; 93018 MW; ED17CF6280FE55EB CRC64;
MSAAVVVCQR RDCGGSYEDV GGGELYCDVC GMAPVVSPQG MVASPPTGIT GQGGPGGSSF
SHGGSSSSHL GSSSSHLGSS SSHLGGYSSR GGDHSSSSGR DSSSGASSRS RSARSSSSRR
SVSGRLSRAM SGRASSRSVS VRSSRSATAA SSARNALGAG LVSVPDVPRP DPRTAVLADP
EVPERKRFCS RGDCGAPVGR ARGERPGRTE GFCTKCGHPY SFVPKLNPGD IVHGQYEIAG
CLAHGGLGWI YLAIDRAVSD RWVVLKGLLD TGDEEALAAA VSERRFLAEI EHSNIVRIYN
FVEHLDQRTG SLDGYIVMEY VGGKSLKDIA NARRTEEGRR DPLPVEQACA YGIEALEALG
HLHSRNLLYC DFKVDNAIQQ QDQLKLIDMG AVRRMDDHDG PIYGTVGYQA PEISETGPSI
ASDLYTVART LAVLTFDFQG YTNVFVDSLP DPEHIEVFRR YESFYRLLVR ATDPDPGRRF
ASAREMADQL TGVLREVVAL QTGRPRPALS TLFGPEPRVV DTELFADDGK DPSLLGSRPI
GGSATAPVPA QRPPGPLALP LPAIATLDGP ATALALPVPL VDSDDPNAGF LAGLLAADPA
EVTAALRTAP VDSVELRLRR VRAQLELGQQ HDAGVALTGL EAAYSDDWRI VWYRGLHSLA
TGDRETAALS FDAVYDAFPG EPAPKLALGV CAELLGQLDN AAEYYRLVWA TDPSFVSAPF
GLARVLLCSG DRAGAVHALE SVPESSIHYT AARVAAVRAR LRQRAPYDAL LGDLAASAVQ
VERLGEFGLD AVRRERLRTE VLGIALDWVL SGSSGAPPGH NRPPLLGSSL DERGLRFGLE
RSYRVLARLA QRGEERIELV ERANRFRPKT WV
//
