ID A0A1P8XVB4_9ACTN Unreviewed; 301 AA.
AC A0A1P8XVB4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=LysR family transcriptional regulator {ECO:0000313|EMBL:AQA12177.1};
GN ORFNames=BV401_18690 {ECO:0000313|EMBL:AQA12177.1};
OS Streptomyces autolyticus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=75293 {ECO:0000313|EMBL:AQA12177.1, ECO:0000313|Proteomes:UP000187851};
RN [1] {ECO:0000313|Proteomes:UP000187851}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC0516 {ECO:0000313|Proteomes:UP000187851};
RA Yin M., Jiang M., Lu T.;
RT "Streptomyces autolyticus CGMCC0516 complete genome sequence.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; CP019458; AQA12177.1; -; Genomic_DNA.
DR RefSeq; WP_069863657.1; NZ_CP019458.1.
DR AlphaFoldDB; A0A1P8XVB4; -.
DR STRING; 75293.BV401_18690; -.
DR KEGG; sauo:BV401_18690; -.
DR OrthoDB; 3673085at2; -.
DR Proteomes; UP000187851; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08423; PBP2_LTTR_like_6; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF16; SMALL NEUTRAL PROTEASE REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 229..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 301 AA; 32726 MW; 41E72C0640CCCB45 CRC64;
MFDSRHIKTF HEVVRSGSYS GAARALGYTQ PAITQQMKAL ERAVGSPLFI RVGRGMRLTE
AGETLARHAD TILTSISTAQ QQMNAITRLR SGRVRVCAFP SANATLIPEA MARLAAAHPG
VRVELLEGEP PESLGRVVRG ECDITLAFTY PGLREETPAE LVEIPLLEDQ LTVLLPTGHP
LARRRAVKLA ELSEERWIAG CLRCRANFLH ECAEQGFAPD IAFTTDDNLV VQSMVAAGLG
VAMMPGLVLS FLCHQKVTGR ALDPASRRRV SAYVLREHLG IPATARVLEE LKTVAANRVG
C
//
