ID A0A1P8Y4H0_9ACTN Unreviewed; 726 AA.
AC A0A1P8Y4H0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=alpha-galactosidase {ECO:0000256|ARBA:ARBA00012755};
DE EC=3.2.1.22 {ECO:0000256|ARBA:ARBA00012755};
GN ORFNames=BV401_37770 {ECO:0000313|EMBL:AQA15302.1};
OS Streptomyces autolyticus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=75293 {ECO:0000313|EMBL:AQA15302.1, ECO:0000313|Proteomes:UP000187851};
RN [1] {ECO:0000313|Proteomes:UP000187851}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC0516 {ECO:0000313|Proteomes:UP000187851};
RA Yin M., Jiang M., Lu T.;
RT "Streptomyces autolyticus CGMCC0516 complete genome sequence.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing alpha-D-galactose
CC residues in alpha-D-galactosides, including galactose
CC oligosaccharides, galactomannans and galactolipids.; EC=3.2.1.22;
CC Evidence={ECO:0000256|ARBA:ARBA00001255};
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DR EMBL; CP019458; AQA15302.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1P8Y4H0; -.
DR STRING; 75293.BV401_37770; -.
DR KEGG; sauo:BV401_37770; -.
DR OrthoDB; 9758822at2; -.
DR Proteomes; UP000187851; Chromosome.
DR GO; GO:0004557; F:alpha-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR CDD; cd14791; GH36; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 2.70.98.60; alpha-galactosidase from lactobacil brevis; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR038417; Alpga-gal_N_sf.
DR InterPro; IPR002252; Glyco_hydro_36.
DR InterPro; IPR031705; Glyco_hydro_36_C.
DR InterPro; IPR031704; Glyco_hydro_36_N.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR43053:SF3; ALPHA-GALACTOSIDASE C-RELATED; 1.
DR PANTHER; PTHR43053; GLYCOSIDASE FAMILY 31; 1.
DR Pfam; PF16874; Glyco_hydro_36C; 1.
DR Pfam; PF16875; Glyco_hydro_36N; 1.
DR Pfam; PF02065; Melibiase; 1.
DR PRINTS; PR00743; GLHYDRLASE36.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 27..267
FT /note="Glycosyl hydrolase family 36 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16875"
FT DOMAIN 628..719
FT /note="Glycosyl hydrolase family 36 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16874"
FT REGION 77..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 726 AA; 78633 MW; C8F9719B8BB2692B CRC64;
MPATPARIVS LRAAGTCFAV ELTEPVPRVL HWGADLGELS PVDLTALSLT AEAATLNNSL
DVPRRFTLWP TEADGWSGTP AHHGHLGGTA TAPRPAMTEA THRADPAGGG ELRVRLAEPA
SGLDITLTYT LDAQGILTAD AVISRGESAD PTPYDLAGAL TLLPLPRRAT EILDFTGKWS
RERSPQRRPL SHGVHSRDVR RGKPGADSPY LLAVGVPGFG YRTGEVWATH VAWSGDQRYL
VEQLPEGAGV HASALGGGEL LRAGEIRLAP GDTYRTPRCH FAWSADGLDG IADRFHGHLR
ARPQHPRGPR PLVLNSWEAV YFDHDLGRLL ALADRAAAVG VERFVLDDGW FSGRRADTAG
LGDWLVDPAV WPDGLGPLAD HVRALGMDFG LWVEPEMVNP DSQLARTHPD WILGPAAGLG
PTARHQYVLD LSRPDVFAYL LKSLDALVGS YDLAYLKWDH NRELHEAVHA GDRPVAHAQV
EALYRLLDAV KQRHPGLEIE SCASGGGRVD LGVLLRTDRV WASDCNDPVE RQAIQSWTVQ
LLPPELVGSH VGAERNHTTG RVTSDTFRTA TALFGHAGIE QDLTECSEAE LARLTAWSAL
YRELRPLLHT GRTVRADLED EARLLHGVVA HDGSRALYCW ARVSTSAEGQ SGRTPLPGLR
PDARYRLRVR TDLGLPSFQQ AAPPPWLTAA VEGWLTLPGA VLATAGLPMP TLNPGQALLI
EVHRQD
//
