ID A0A1P8YG51_9NOCA Unreviewed; 383 AA.
AC A0A1P8YG51;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Acetyl-CoA C-acetyltransferase family protein {ECO:0000313|EMBL:AQA23094.1};
GN ORFNames=BTZ20_0634 {ECO:0000313|EMBL:AQA23094.1};
OS Rhodococcus sp. MTM3W5.2.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=1805827 {ECO:0000313|EMBL:AQA23094.1, ECO:0000313|Proteomes:UP000187995};
RN [1] {ECO:0000313|EMBL:AQA23094.1, ECO:0000313|Proteomes:UP000187995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MTM3W5.2 {ECO:0000313|EMBL:AQA23094.1,
RC ECO:0000313|Proteomes:UP000187995};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP019572; AQA23094.1; -; Genomic_DNA.
DR RefSeq; WP_077040304.1; NZ_CP019572.1.
DR AlphaFoldDB; A0A1P8YG51; -.
DR STRING; 1805827.BTZ20_0634; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000187995; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:AQA23094.1}.
FT DOMAIN 5..251
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 261..381
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 89
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 338
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 368
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 383 AA; 40028 MW; 6F0EDD686B165102 CRC64;
MAEAYIVDAV RTAVGRKNGA LSAVHPIDLG ASVIRSLTDR NPIDPAAIDD VMFGCVDTIG
GQAGNIARTS ALAAGLPEGV PGVTVDRQCG SSQQALHFAA QAVLSGTADL IVAGGVQSMS
RIPISAAMTA GREFGFDDPY SGSEDWRRRY GNTEISQFRA AELIAEKWGI SRLEMEQWAL
RSHQRARDAI AGGRFDGEIV PVGSFEVDEC PRDTSLAKMA ALPPLREGGR LTAALASQIS
DGASAVLVAS AAALKTHNLV PRARIHHLSA RGADPVFMLT APIPATEYAL GKTGMSIDDF
DVIEINEAFA SVVLAWLAET GADPERVNVN GGGIALGHPL GATGTKLFGT LLNELERTGG
RYGLQTMCEG GGTANVLIVE RLG
//
