ID A0A1P8YIT8_9NOCA Unreviewed; 301 AA.
AC A0A1P8YIT8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=2,3-dihydroxybiphenyl 1,2-dioxygenase {ECO:0000313|EMBL:AQA24019.1};
DE EC=1.13.11.39 {ECO:0000313|EMBL:AQA24019.1};
GN ORFNames=BTZ20_0057 {ECO:0000313|EMBL:AQA24019.1};
OS Rhodococcus sp. MTM3W5.2.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=1805827 {ECO:0000313|EMBL:AQA24019.1, ECO:0000313|Proteomes:UP000187995};
RN [1] {ECO:0000313|EMBL:AQA24019.1, ECO:0000313|Proteomes:UP000187995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MTM3W5.2 {ECO:0000313|EMBL:AQA24019.1,
RC ECO:0000313|Proteomes:UP000187995};
RA Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954,
CC ECO:0000256|RuleBase:RU000683};
CC -!- SIMILARITY: Belongs to the extradiol ring-cleavage dioxygenase family.
CC {ECO:0000256|ARBA:ARBA00008784, ECO:0000256|RuleBase:RU000683}.
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DR EMBL; CP019572; AQA24019.1; -; Genomic_DNA.
DR RefSeq; WP_077039962.1; NZ_CP019572.1.
DR AlphaFoldDB; A0A1P8YIT8; -.
DR STRING; 1805827.BTZ20_0057; -.
DR OrthoDB; 6909416at2; -.
DR Proteomes; UP000187995; Chromosome.
DR GO; GO:0018583; F:biphenyl-2,3-diol 1,2-dioxygenase activity; IEA:UniProtKB-EC.
DR GO; GO:0008198; F:ferrous iron binding; IEA:InterPro.
DR GO; GO:0004462; F:lactoylglutathione lyase activity; IEA:InterPro.
DR GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0042178; P:xenobiotic catabolic process; IEA:InterPro.
DR CDD; cd07237; BphC1-RGP6_C_like; 1.
DR CDD; cd07252; BphC1-RGP6_N_like; 1.
DR Gene3D; 3.10.180.10; 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1; 2.
DR InterPro; IPR017626; DiOHbiphenyl_dOase.
DR InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR InterPro; IPR004360; Glyas_Fos-R_dOase_dom.
DR InterPro; IPR018146; Glyoxalase_1_CS.
DR InterPro; IPR037523; VOC.
DR InterPro; IPR000486; Xdiol_ring_cleave_dOase_1/2.
DR NCBIfam; TIGR03213; 23dbph12diox; 1.
DR PANTHER; PTHR21366; GLYOXALASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR21366:SF34; IRON-DEPENDENT EXTRADIOL DIOXYGENASE; 1.
DR Pfam; PF00903; Glyoxalase; 1.
DR SUPFAM; SSF54593; Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase; 1.
DR PROSITE; PS00082; EXTRADIOL_DIOXYGENAS; 1.
DR PROSITE; PS00934; GLYOXALASE_I_1; 1.
DR PROSITE; PS51819; VOC; 2.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797,
KW ECO:0000256|RuleBase:RU000683};
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964, ECO:0000256|RuleBase:RU000683};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU000683};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000683}.
FT DOMAIN 6..121
FT /note="VOC"
FT /evidence="ECO:0000259|PROSITE:PS51819"
FT DOMAIN 143..268
FT /note="VOC"
FT /evidence="ECO:0000259|PROSITE:PS51819"
SQ SEQUENCE 301 AA; 32857 MW; 8CFACC95B2B9FB33 CRC64;
MTDIKGLGYI KVQTNDMERW RKFAFDVLGF AEGSGPDENA IYLRMDERAA RIVIVPGDTD
EVVTIGWEVR DHAALVRVQE AVEAAGIAVK PLSLEEADAR RVEEVITFQD PTGATLEIFH
GAVLDHSPVV TPFGAKFVTG AQGLGHVVLP VMDINGAFAF YTEVLGFLPR GAFRIPAPPE
FGPMRVRFMG VNERHHSLAL CPAPHGGAPG LVHIMVEVDT LDAVGQALDR VVKDGFSVSS
TLGRHTNDKM VSFYVRAPGG WDIEFGTEGM RVDEKYYSAE EITADSYWGH DWSGSEPLAA
M
//
