ID A0A1Q1FNW7_9EURY Unreviewed; 378 AA.
AC A0A1Q1FNW7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=ORC1-type DNA replication protein {ECO:0000256|HAMAP-Rule:MF_01407};
GN Name=cdc6 {ECO:0000313|EMBL:AQL44530.1};
GN ORFNames=BV210_09740 {ECO:0000313|EMBL:AQL44530.1};
OS Halorientalis sp. IM1011.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halorientalis.
OX NCBI_TaxID=1932360 {ECO:0000313|EMBL:AQL44530.1, ECO:0000313|Proteomes:UP000187924};
RN [1] {ECO:0000313|EMBL:AQL44530.1, ECO:0000313|Proteomes:UP000187924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IM1011 {ECO:0000313|EMBL:AQL44530.1,
RC ECO:0000313|Proteomes:UP000187924};
RA Zhao D., Kumar S., Zhou J., Wang R., Xiang H.;
RT "Isolation and genome sequence of Halorientalis hydrocarbonoclasticus sp.
RT nov., a hydrocarbon-degrading haloarchaeon.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in regulation of DNA replication.
CC {ECO:0000256|HAMAP-Rule:MF_01407}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000256|HAMAP-
CC Rule:MF_01407}.
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DR EMBL; CP019067; AQL44530.1; -; Genomic_DNA.
DR RefSeq; WP_077208029.1; NZ_CP019067.1.
DR AlphaFoldDB; A0A1Q1FNW7; -.
DR STRING; 1932360.BV210_09740; -.
DR GeneID; 30959977; -.
DR KEGG; hali:BV210_09740; -.
DR OrthoDB; 53276at2157; -.
DR Proteomes; UP000187924; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR015163; Cdc6_C.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR PANTHER; PTHR10763:SF32; ORC1-TYPE DNA REPLICATION PROTEIN 2; 1.
DR Pfam; PF13191; AAA_16; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01074; Cdc6_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_01407}; Cell cycle {ECO:0000313|EMBL:AQL44530.1};
KW Cell division {ECO:0000313|EMBL:AQL44530.1};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705, ECO:0000256|HAMAP-
KW Rule:MF_01407};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_01407}; Reference proteome {ECO:0000313|Proteomes:UP000187924}.
FT DOMAIN 54..211
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 304..376
FT /note="Cdc6 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01074"
FT BINDING 66..70
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 210
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 222
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
SQ SEQUENCE 378 AA; 42697 MW; 69E736D6ACCBDD54 CRC64;
MTDDPEEGML SWDESVFRDE HVFEIDYLPE TFHHRDSQME SLKYALRPAV RGSRPLNVVA
RGPPGTGKTT AIQKLFTELR AETTDVRAVR VNCQVNGTRY SVFSRLFEGI FDYEPPSSGI
SFKRLFEQVT DRLVDDEEVL VVALDDVNYL FYENEASDTL YSLLRAHEEH AGAKIGVICI
SSDLDLDVIE ELDGRVQSVF RPEEVYFPKY DESEIVDILN ERVDRGFHDG VISPRELDRV
AELTAESNGD LRVGIDLLRR AGLNAEMRAS TEVSVEDVEE AYDKSKFVHL SRALQGLSDS
EAALVAVIAE HSGEQAGDVY DTFNDRTDLG YTRYSEIINK LDRLGIIDAT YTDVDGRGRS
RELTLNYDAD AVLDRLET
//
