ID A0A1Q1PN01_9VIRU Unreviewed; 132 AA.
AC A0A1Q1PN01;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Sulfhydryl oxidase {ECO:0000256|RuleBase:RU371123};
DE EC=1.8.3.2 {ECO:0000256|RuleBase:RU371123};
GN ORFNames=NMV_144 {ECO:0000313|EMBL:AQM73125.1};
OS Noumeavirus.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Pimascovirales; Marseilleviridae; Marseillevirus.
OX NCBI_TaxID=1955558 {ECO:0000313|EMBL:AQM73125.1, ECO:0000313|Proteomes:UP000203865};
RN [1] {ECO:0000313|EMBL:AQM73125.1, ECO:0000313|Proteomes:UP000203865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NMV1 {ECO:0000313|EMBL:AQM73125.1};
RA Fabre E., Santini S., Legendre M., Bruley C., Coute Y., Claverie J.-M.,
RA Abergel C., Jeudy S.;
RT "The proteome of Melbournevirus and Noumeavirus virions unveil a nucleo-
RT cytoplasmic infectious cycle of Marseilleviridae.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=O2 + 2 R'C(R)SH = H2O2 + R'C(R)S-S(R)CR';
CC Xref=Rhea:RHEA:17357, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC ChEBI:CHEBI:16520, ChEBI:CHEBI:17412; EC=1.8.3.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000999,
CC ECO:0000256|RuleBase:RU371123};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|RuleBase:RU371123};
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DR EMBL; KX066233; AQM73125.1; -; Genomic_DNA.
DR Proteomes; UP000203865; Genome.
DR GO; GO:0016971; F:flavin-dependent sulfhydryl oxidase activity; IEA:InterPro.
DR Gene3D; 1.20.120.310; ERV/ALR sulfhydryl oxidase domain; 1.
DR InterPro; IPR039799; ALR/ERV.
DR InterPro; IPR036774; ERV/ALR_sulphydryl_oxid_sf.
DR InterPro; IPR017905; ERV/ALR_sulphydryl_oxidase.
DR PANTHER; PTHR12645; ALR/ERV; 1.
DR PANTHER; PTHR12645:SF0; FAD-LINKED SULFHYDRYL OXIDASE ALR; 1.
DR Pfam; PF04777; Evr1_Alr; 1.
DR SUPFAM; SSF69000; FAD-dependent thiol oxidase; 1.
DR PROSITE; PS51324; ERV_ALR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU371123};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU371123};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU371123}.
FT DOMAIN 18..117
FT /note="ERV/ALR sulfhydryl oxidase"
FT /evidence="ECO:0000259|PROSITE:PS51324"
SQ SEQUENCE 132 AA; 15609 MW; 4F9A3B5B56714D3E CRC64;
MRQVKRQVRP TPQPMRQTGE NKEFWGPCLW RTIHSFAATY TPEKAQEFSA FMLSLQNLLP
CTTCKDNYRK NLRELPPLRN FLGSRDRVFY WTYLLHDKVN KELGKQSPPF QKVREVYFDR
LTGKGSCSSC KN
//
