ID A0A1Q2CD10_9ACTN Unreviewed; 441 AA.
AC A0A1Q2CD10;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Glutamine synthetase {ECO:0000313|EMBL:AQP43994.1, ECO:0000313|EMBL:SDY31350.1};
GN ORFNames=RPIT_03500 {ECO:0000313|EMBL:AQP43994.1}, SAMN05428934_101300
GN {ECO:0000313|EMBL:SDY31350.1};
OS Tessaracoccus flavus.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Tessaracoccus.
OX NCBI_TaxID=1610493 {ECO:0000313|EMBL:AQP43994.1, ECO:0000313|Proteomes:UP000188324};
RN [1] {ECO:0000313|EMBL:AQP43994.1, ECO:0000313|Proteomes:UP000188324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RP1T {ECO:0000313|EMBL:AQP43994.1,
RC ECO:0000313|Proteomes:UP000188324};
RX PubMed=26869509; DOI=10.1099/ijsem.0.000958;
RA Kumari R., Singh P., Schumann P., Lal R.;
RT "Tessaracoccus flavus sp. nov., isolated from the drainage system of a
RT lindane-producing factory.";
RL Int. J. Syst. Evol. Microbiol. 66:1862-1868(2016).
RN [2] {ECO:0000313|EMBL:SDY31350.1, ECO:0000313|Proteomes:UP000199635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RP1 {ECO:0000313|EMBL:SDY31350.1,
RC ECO:0000313|Proteomes:UP000199635};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AQP43994.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RP1T {ECO:0000313|EMBL:AQP43994.1};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
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DR EMBL; CP019605; AQP43994.1; -; Genomic_DNA.
DR EMBL; FNPU01000001; SDY31350.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q2CD10; -.
DR STRING; 1610493.RPIT_03500; -.
DR KEGG; tfl:RPIT_03500; -.
DR OrthoDB; 9807095at2; -.
DR Proteomes; UP000188324; Chromosome.
DR Proteomes; UP000199635; Unassembled WGS sequence.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.10.20.70; Glutamine synthetase, N-terminal domain; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR036651; Gln_synt_N_sf.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR PANTHER; PTHR43785; GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE; 1.
DR PANTHER; PTHR43785:SF11; GLUTAMINE SYNTHETASE; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR Pfam; PF03951; Gln-synt_N; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF54368; Glutamine synthetase, N-terminal domain; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000188324}.
FT DOMAIN 15..100
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 107..441
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 441 AA; 49989 MW; 704EDA93CD597EBE CRC64;
MDRQTEFVLR SMEERGIRFV RLWFTDVLGS LKSVAIAPAE VEGAIAEGVG FDGSAIEGFA
RVFESDMVAH PDPSTYQVLP WREGGRSTAR MLCDIRLPDG SPSFADPRYV LKRALDGAGR
KGFTFYIHPE IEFFLLRTLN PPTPLDEGGY FDHTTLGDGT DFRRDAITML EQMGISVEFS
HHEAAPGQHE IDLRYADALT MADNVMTFRV VIREVAVSQG IHASFMPKPF SEHPGSGMHT
HMSLFEGDTN AFYDAADEYH LSKTAKQFIA GLLRHAPEIT AVTNQWVNSY KRLVGGDEAP
SYACWGRSNR SALIRIPQFT PGKTSSARIE YRAVDAAVNP YLAYALMLNA GLKGIEEEYQ
LPEETEDEVW RLTDRERQAI GIRELPRNLD QALRLMEESE VVAETLGEHV FEYFLRNKRE
EFAVYRRQVT PWELERHIRV M
//
