ID A0A1Q2CQN9_9ACTN Unreviewed; 299 AA.
AC A0A1Q2CQN9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Rhomboid family intramembrane serine protease {ECO:0000313|EMBL:AQP48427.1};
GN ORFNames=BW730_13835 {ECO:0000313|EMBL:AQP48427.1};
OS Tessaracoccus aquimaris.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Tessaracoccus.
OX NCBI_TaxID=1332264 {ECO:0000313|EMBL:AQP48427.1, ECO:0000313|Proteomes:UP000188145};
RN [1] {ECO:0000313|Proteomes:UP000188145}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NSG39 {ECO:0000313|Proteomes:UP000188145};
RA Tak E.J., Bae J.-W.;
RT "Tessaracoccus aquaemaris sp. nov., isolated from the intestine of a Korean
RT rockfish, Sebastes schlegelii, in a marine aquaculture pond.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase S54 family.
CC {ECO:0000256|ARBA:ARBA00009045}.
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DR EMBL; CP019606; AQP48427.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q2CQN9; -.
DR STRING; 1332264.BW730_13835; -.
DR KEGG; tes:BW730_13835; -.
DR OrthoDB; 9807874at2; -.
DR Proteomes; UP000188145; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1540.10; Rhomboid-like; 1.
DR InterPro; IPR022764; Peptidase_S54_rhomboid_dom.
DR InterPro; IPR035952; Rhomboid-like_sf.
DR InterPro; IPR000315; Znf_B-box.
DR PANTHER; PTHR43731:SF26; RHOMBOID DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43731; RHOMBOID PROTEASE; 1.
DR Pfam; PF01694; Rhomboid; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF144091; Rhomboid-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:AQP48427.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000313|EMBL:AQP48427.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000188145};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 71..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..32
FT /note="B box-type"
FT /evidence="ECO:0000259|Pfam:PF00643"
FT DOMAIN 133..267
FT /note="Peptidase S54 rhomboid"
FT /evidence="ECO:0000259|Pfam:PF01694"
SQ SEQUENCE 299 AA; 31931 MW; 2821479A844B74AC CRC64;
MDDASTCYRH PDQPTRIRCQ RCDRPICPQC MVPGSVGFQC PECVARGMKE TRQNELPHGG
KRSANPRGTS IALIGINVAV WVAILLTGWS NSRLVNLLAL TPNGVCASPD QYVPGATPAT
CTIPGFEWSD GVASGAFWQV ITSGFTHVGI THIGFNMLVL WMLGPNMEQN LGRVRYLAVY
LVALLGGSAA VMLFSDPETA TLGASGAIYG LMGALVVLAV RYKGNVQQIL IWLGINVAIS
FTFPGISWQG HFGGLLGGAL VAAILVYLPK DKRNLQWPLV GLVAAVFIGL VVTRALQLA
//
