ID A0A1Q2CUA1_9ACTN Unreviewed; 216 AA.
AC A0A1Q2CUA1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Precorrin-8X methylmutase {ECO:0000313|EMBL:AQP49674.1};
GN Name=cobH {ECO:0000313|EMBL:AQP49674.1};
GN ORFNames=BW733_01335 {ECO:0000313|EMBL:AQP49674.1};
OS Tessaracoccus flavescens.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Tessaracoccus.
OX NCBI_TaxID=399497 {ECO:0000313|EMBL:AQP49674.1, ECO:0000313|Proteomes:UP000188235};
RN [1] {ECO:0000313|EMBL:AQP49674.1, ECO:0000313|Proteomes:UP000188235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SST-39T {ECO:0000313|EMBL:AQP49674.1,
RC ECO:0000313|Proteomes:UP000188235};
RX PubMed=18398170; DOI=10.1099/ijs.0.64868-0;
RA Lee D.W., Lee S.D.;
RT "Tessaracoccus flavescens sp. nov., isolated from marine sediment.";
RL Int. J. Syst. Evol. Microbiol. 58:785-789(2008).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
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DR EMBL; CP019607; AQP49674.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q2CUA1; -.
DR STRING; 399497.BW733_01335; -.
DR KEGG; tfa:BW733_01335; -.
DR OrthoDB; 9780708at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000188235; Chromosome.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000188235}.
FT DOMAIN 10..205
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 216 AA; 22715 MW; 4BB4BF65E79977F3 CRC64;
MPDYLRTGEE IYEESFRIIR AETNLARFPA DVSRAVVRMV HAAGATDIAD DVNFTPGVVA
AANTALRAGA PIFCDSSMVS TGIIRSRLPR DNDVICHIKD PALVEIAAAR GITKTMAAVD
LWLPRLEGAV VAVGNAPTAL FRLLEIVAET GARPAAVIGI PVGFVGAAES KEALVANPFG
LDYLVVRGRR GGSAMTVAAV NAIASTDELT NTSRQD
//
