ID A0A1Q2CVI3_9ACTN Unreviewed; 493 AA.
AC A0A1Q2CVI3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN ORFNames=BW733_03855 {ECO:0000313|EMBL:AQP50097.1};
OS Tessaracoccus flavescens.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Tessaracoccus.
OX NCBI_TaxID=399497 {ECO:0000313|EMBL:AQP50097.1, ECO:0000313|Proteomes:UP000188235};
RN [1] {ECO:0000313|EMBL:AQP50097.1, ECO:0000313|Proteomes:UP000188235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SST-39T {ECO:0000313|EMBL:AQP50097.1,
RC ECO:0000313|Proteomes:UP000188235};
RX PubMed=18398170; DOI=10.1099/ijs.0.64868-0;
RA Lee D.W., Lee S.D.;
RT "Tessaracoccus flavescens sp. nov., isolated from marine sediment.";
RL Int. J. Syst. Evol. Microbiol. 58:785-789(2008).
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DR EMBL; CP019607; AQP50097.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q2CVI3; -.
DR STRING; 399497.BW733_03855; -.
DR KEGG; tfa:BW733_03855; -.
DR OrthoDB; 2339873at2; -.
DR Proteomes; UP000188235; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002641; PNPLA_dom.
DR PANTHER; PTHR14226:SF29; NEUROPATHY TARGET ESTERASE SWS; 1.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000188235}.
FT DOMAIN 23..313
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
FT REGION 120..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..160
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 493 AA; 54223 MW; E6B4503064CF2EB0 CRC64;
MAGKGWFGLP FFSLNPRPEV VSCVLSGGGS RASFQLGALD YLYRHDEQFT PTIFVGASAG
SILASTLAQS ADRDVQQEYL RRLREIWDAM TEPNDMFTPR PWYERLATEG PQLLELVKPL
RTDPRPAPPR PQRAPLLPFL RQSPASPPTP ELPPQPTPLE LALTPDSDEP VRSEWSLAAL
SSIASHLGRL PRIGSDLNAI AHGLDASKSM YRPGPVLLEL LREETFFPAR VAASGATLRI
AMVALESGEL RFMTERGSFV NRNNEPLPGG LHDLTIGVLA SCAIPAVFRP VPIGNETYVD
GGVRENLPAA LAIGHLGAVR NYVVSSQSSG VHRRGSMADA DLFSIVMRST EILIDEAGRD
ELAYAHSAGS IVIYPELSVH DAMTVDPALI AINEAYGWLR AAEQHLHLDQ AAEARHRRII
EARLRALQAE QDYLSTEEPD KRRLRALRSA KTELRDAVRS ARDVPLPPGA EEWWRTWEPR
ATPVALDPPW LTA
//
