ID A0A1Q2D5R9_9ENTE Unreviewed; 459 AA.
AC A0A1Q2D5R9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN ORFNames=BW732_05300 {ECO:0000313|EMBL:AQP53712.1};
OS Vagococcus penaei.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Vagococcus.
OX NCBI_TaxID=633807 {ECO:0000313|EMBL:AQP53712.1, ECO:0000313|Proteomes:UP000188246};
RN [1] {ECO:0000313|EMBL:AQP53712.1, ECO:0000313|Proteomes:UP000188246}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CD276 {ECO:0000313|EMBL:AQP53712.1,
RC ECO:0000313|Proteomes:UP000188246};
RX PubMed=19897618; DOI=10.1099/ijs.0.012872-0;
RA Jaffres E., Prevost H., Rossero A., Joffraud J.J., Dousset X.;
RT "Vagococcus penaei sp. nov., isolated from spoilage microbiota of cooked
RT shrimp (Penaeus vannamei).";
RL Int. J. Syst. Evol. Microbiol. 60:2159-2164(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
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DR EMBL; CP019609; AQP53712.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q2D5R9; -.
DR STRING; 633807.BW732_05300; -.
DR KEGG; vpi:BW732_05300; -.
DR Proteomes; UP000188246; Chromosome.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF1; ISOCHORISMATE SYNTHASE MENF; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000188246}.
FT DOMAIN 193..446
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 459 AA; 50876 MW; 4CE856B196C5451A CRC64;
MEVTELDKVK ALLEDGQDYV SLVVSESKQS LTPLAYFQGS DTHNIPERWY FETPDRQSAY
AGFGSVKTLT GGDAQADAIR LWGQKQRVVT IPIEHQPVAM PQLVGALSFM PYAEEDEIWG
ELSRGYFFVP SIQVMQLADK LINVINFSQE DKLSLDQVAQ ERLALLHKLE QTAQHFVNQT
VTVINEREVG VTDWLELVER GVSTIKSHEG LDKVVVARTL ELETAEILSI PTVVTQLREQ
QPNIYVFALT YGTKGFVGAT PERLLKATDE TFMTASVAGS TPRGVTQEED SRLGQQLLND
MKNRGEHRIV VDRIVADLEN LSGTPIQLAK PSLLKNRDIQ HLFLPIEASR ATDTSLLDGI
IALHPTPALG GEPKDKALAF LAQYEPFQRG LYGAPIGWYG LGQDIGEFVV GIRSALIDGE
KSVLYAGCGI VAESEPELER QETRVKFQPM RRGIGGMEQ
//
