ID   A0A1Q2GZI6_9GAMM        Unreviewed;       333 AA.
AC   A0A1Q2GZI6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=UDP-N-acetylglucosamine 4,6-dehydratase (Inverting) {ECO:0000313|EMBL:AQQ00544.1};
GN   ORFNames=B0W48_12470 {ECO:0000313|EMBL:AQQ00544.1};
OS   Pseudoalteromonas aliena.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=247523 {ECO:0000313|EMBL:AQQ00544.1, ECO:0000313|Proteomes:UP000188243};
RN   [1] {ECO:0000313|EMBL:AQQ00544.1, ECO:0000313|Proteomes:UP000188243}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EH1 {ECO:0000313|EMBL:AQQ00544.1,
RC   ECO:0000313|Proteomes:UP000188243};
RA   Kim E., Heo E., Kim H., Kim D.;
RT   "Complete genome sequence of the cold-active Pseudoalteromonas aliena
RT   strain EH1 isolated from Arctic seawater.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=UDP-alpha-D-glucose = UDP-alpha-D-galactose;
CC         Xref=Rhea:RHEA:22168, ChEBI:CHEBI:58885, ChEBI:CHEBI:66914;
CC         EC=5.1.3.2; Evidence={ECO:0000256|ARBA:ARBA00000083};
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; CP019628; AQQ00544.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q2GZI6; -.
DR   STRING; 247523.B0W48_12470; -.
DR   KEGG; paln:B0W48_12470; -.
DR   Proteomes; UP000188243; Chromosome.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   InterPro; IPR020025; PseB.
DR   NCBIfam; TIGR03589; PseB; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   PANTHER; PTHR43318:SF2; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE (INVERTING); 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
FT   DOMAIN          7..279
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   333 AA;  37600 MW;  5854D6CBC6C3312A CRC64;
     MFNGKVVFIT GGTGSFGKKY VKTLLERYQP KKIIIFSRDE LKQFEMQQEF DQPCMRYFIG
     DVRDKARLQR AMRGVDYVIH AAALKQVPAA EYNPMECIKT NINGAENVID AALDNNVEKV
     IALSTDKAAN PINLYGATKL ASDKLFIAAN NIAGGHRTTF SVVRYGNVVC SRGSVVPIFQ
     KFIDEGRDHI PITHLEMTRF WINLQQGVDF VLTNFERMLG GEIFVPKIPS IRIIDLAKAM
     APDLPIKDIG IRPGEKLHEV MCPADLCFET YEYHDHYLIA PGIKFSSRSN DFTVNAIGEK
     GHKVPQGFEY NSLNNHHYMS IDDIKMFNTQ ALL
//