ID   A0A1Q2H0N7_9GAMM        Unreviewed;       848 AA.
AC   A0A1Q2H0N7;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=B0W48_14695 {ECO:0000313|EMBL:AQQ00917.1};
OS   Pseudoalteromonas aliena.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=247523 {ECO:0000313|EMBL:AQQ00917.1, ECO:0000313|Proteomes:UP000188243};
RN   [1] {ECO:0000313|EMBL:AQQ00917.1, ECO:0000313|Proteomes:UP000188243}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EH1 {ECO:0000313|EMBL:AQQ00917.1,
RC   ECO:0000313|Proteomes:UP000188243};
RA   Kim E., Heo E., Kim H., Kim D.;
RT   "Complete genome sequence of the cold-active Pseudoalteromonas aliena
RT   strain EH1 isolated from Arctic seawater.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR   EMBL; CP019628; AQQ00917.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q2H0N7; -.
DR   STRING; 247523.B0W48_14695; -.
DR   KEGG; paln:B0W48_14695; -.
DR   Proteomes; UP000188243; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF63; DNA HELICASE IV; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}.
FT   DOMAIN          189..653
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         210..217
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   848 AA;  97256 MW;  91C31B098D4BA4C9 CRC64;
     MAQYIATPSW LGRFFTRIKQ VSIEQSMLVI DFRDNTNLQF RLSDFSNFSM LRNRLFSAEI
     NLSDLNNTCI SFLNKGQADV LSKALNHYFA NSLEQKINKA KTQLKQYALD EFLRDSSIEI
     LNKTVFSLSK NYAHNQILWQ QHLSPVSIKF LSILSRTPKV TDAVAQLRHK YEQKQLTLRD
     NFYNNVESNP LTIEQRLAVI RDNDKNLVLA AAGTGKTSVM VAKSLDLIDR DIATPDQILV
     LAYNKAAAEE LKERFIKRAG QANLSMTPPV ILTFHALGLT LLRNAKKSTE LSVLASDALQ
     LKSWFTAWLS EQMQANSAFL KSFVDLLYEP VDIFSFKNSA EDEHYVRINE YKSFAGYKVK
     SYQELLISNW LHLNSVEHEY KPAYKIKQRV GPGDKRLNKQ YSSFYLPKYN IYLDHYDIDR
     QSNTPSGINK EHYNEHIALK RELYKKDNTI FLETFHFNWL EGKLEQRLGK LLKQYSVALT
     PLADDKIFAL LTNSGQLQQE AEKYLKCLQA IRVEQLTNTQ IKQRIKQSGF KNHQRYAAML
     ITIHDAYTHE LSRQNAIDFD DMVIHATQVV KKGEFSVPWS HILVDEFQDI SGARMAFLNT
     LINKGTGIRF TAVGDDWQAI YRFSGGNLAL TTRFEELVGS HSLTVLQKTF RYNNSISDVA
     GRFVMQNPEQ YKKHITTHVQ VSTPQVILLD DQYKGAKSLE VKVQQIISTI QKNDATASIA
     VLSRYRFMLN KVEQHLKNKK QTNTLHFWTL HGAKGLEADY GIIIGFEQGK LGFPSNNQNN
     VLLESLLPVQ DSFTHSEERR LLYVGITRAK HKTYLIADLH ACSVFIKELV NDDYPIEVAS
     TLFNLSSG
//